Tag:

neuroinflammation

Dementia
Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants

by myneuronews September 7, 2025

by myneuronews September 7, 2025

Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in …

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Dementia
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression …

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Traumatic brain injury
Probiotics Co-administered with LCM Enhance Antiepileptic Efficacy in the Experimental Post-traumatic Epilepsy Model

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview The investigation focused on the synergistic effects of probiotics when administered alongside levetiracetam …

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Functional neurological disorders
Advances in functional Neurological disorder

by myneuronews September 5, 2025

by myneuronews September 5, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex and intriguing challenge …

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Traumatic brain injury
The Role of MRI in Debunking the Fallacy of “Mild” Traumatic Brain Injury

by myneuronews September 5, 2025

by myneuronews September 5, 2025

The Importance of MRI in TBI Assessment Magnetic Resonance Imaging (MRI) plays a pivotal role …

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Functional neurological disorders
Somatic Symptom and Related Disorders and Mild Traumatic Brain Injury: A Systematic Review

by myneuronews September 2, 2025

by myneuronews September 2, 2025

Somatic Symptom Overview Somatic symptom disorders encompass a range of conditions characterized by the presence …

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Dementia
Emerging Role of Oligodendrocytes Malfunction in the Progression of Alzheimer’s Disease

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Oligodendrocyte Function and Alzheimer’s Disease Oligodendrocytes are specialized glial cells in the central nervous system, …

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Headaches
Intranasal Empagliflozin Modulates Synaptic Plasticity in Migraine: Insights into Calcium Signaling and Epigenetic Regulation

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Mechanisms of Action Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, primarily functions by reducing glucose …

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Traumatic brain injury
Associations between traumatic brain injury and the prevalence of Alzheimer’s disease dementia and behavioral and psychological symptoms of dementia: A retrospective cohort study

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Associations between TBI and Alzheimer’s Disease Traumatic brain injury (TBI) has garnered significant interest as …

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Traumatic brain injury
Chronic traumatic encephalopathy

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition associated with …

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Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium
CONCLUSIONS: These findings collectively identify COL4A1 deficiency as a sensitizing factor for post-traumatic visual dysfunction and demonstrate that ASC-CCM exerts therapeutic effects by preserving retinal vascular structure and modulating inflammatory responses, positioning it as a promising candidate for treating TBI-related ocular neurovascular injury.
Hollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury
Traumatic brain injury (TBI) remains a significant global health burden and demands rapid, objective diagnostics that work outside imaging suites and intensive lab workflows. Here, we developed a copper sulfide (CuS) nanocube-assisted laser desorption/ionization mass spectrometry (LDI-MS) platform to acquire serum metabolic profiles (SMPs) with high sensitivity, low background in the low-m/z region, and excellent […]
Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study
Introduction This study examines whether attention-deficit/hyperactivity disorder (ADHD) can develop after traumatic brain injury in children. Overlapping acute symptoms can hinder early identification and diagnosis. We investigated whether demographic or acute clinical features are associated with the development of secondary ADHD (S-ADHD) following mild pediatric traumatic brain injury. Materials and methods We conducted a retrospective […]
Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic brain injury
CONCLUSION: The whiteout sign was strongly associated with being in the symptomatic group and is a potential biomarker for recognition of secondary changes to the brain in patients with persistent symptoms following TBI.
Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint
Transcranial direct current stimulation (tDCS) for painless, non-invasive brain stimulation is a promising approach to enhance recovery after stroke. However, the precise molecular and cellular mechanisms underlying the effects of tDCS remain unclear, impeding its use in humans and necessitating research in experimental animals. Unlike humans, who receive tDCS fully awake, experimental models of tDCS […]