Tag:

neuroinflammation

Functional neurological disorders
A 2025 update on treatment strategies for the Alzheimer’s disease spectrum

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Treatment Approaches The treatment landscape for Alzheimer’s disease has evolved considerably, reflecting a multifaceted …

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Traumatic brain injury
Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Biomarkers in Traumatic Brain Injury Biomarkers are measurable indicators in the body that can reflect …

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Traumatic brain injury
Combination Therapy of Estrogen and Progesterone Attenuates Behavioral Impairments and Autophagy via circLrp1b/miR-27a-3p/Dram2 Pathway After Traumatic Brain Injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Study Overview The research investigates the effects of combination therapy involving estrogen and progesterone in …

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Traumatic brain injury
Impact of prior exposures on biomarkers of blast during military tactical training

by myneuronews May 28, 2025

by myneuronews May 28, 2025

Study Overview This investigation aims to examine how prior exposures, particularly to blast injuries, influence …

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Functional neurological disorders
Deficits of Alzheimer’s Disease Neuropsychological Architecture Correlate with Specific Exosomal mRNA Expression: Evidence of a Continuum?

by myneuronews May 28, 2025

by myneuronews May 28, 2025

Neuropsychological Deficits in Alzheimer’s Disease Alzheimer’s disease (AD) is often characterized by a progressive decline …

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Functional neurological disorders
Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Immune Mechanisms in Anti-NMDAR Encephalitis Anti-NMDAR encephalitis is characterized by the presence of antibodies that …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Material and Methods The study on fully biodegradable dendrimers as novel nanodrugs targeting amyloid-β-induced neurotoxicity …

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Traumatic brain injury
Exercise plasma improves traumatic brain injury outcomes in mice

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Effects of Exercise Plasma on Brain Injury Research has shown that exercise can have profound …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Biodegradable Dendrimers: A Novel Approach Dendrimers are highly branched molecules that can be customized at …

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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that…
Collaborative Community Support for People Impacted by Dementia: A Social Return on Investment Analysis
Study Overview This research focuses on understanding the impact of a community-based support program designed…
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Cognitive Fatigue in Pediatric Populations Cognitive fatigue is a significant concern in pediatric populations, particularly…
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the…
ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Study Overview The study focuses on enhancing the accuracy of brain lesion parcellation, a crucial…

Substrate-selective COX-2 inhibition by IMMA attenuates posttraumatic headache via endocannabinoid modulation and neuroinflammatory suppression
CONCLUSION: IMMA effectively attenuates neuroinflammation and pain hypersensitivity in the acute phase of PTH through a distinct mechanism that preserves endocannabinoid tone without suppressing physiological prostaglandins. While these results highlight its promise as a novel therapeutic strategy, further studies are warranted to determine its efficacy during the chronic phase of PTH and across anatomically targeted […]
Intensive exposure therapy for individuals with persistent concussion symptoms following concussion: a replicated single-case experimental design (SCED) study
CONCLUSIONS: The findings of this study further confirmed the efficacy for this intensive exposure therapy for PCS, adding further evidence for exposure therapy in this patient population. Replication in other samples is needed.
Sensory integration processes characterize concussed athletes with balance deficits
Impaired postural control constitutes a major symptom after mild traumatic brain injuries (mTBI/sport-related concussions (SRC)). In order to uphold cognition and behavior during pathological situations, individuals may be characterized by neuronal upregulation. Because postural control necessitates the integration of sensory information within somatosensory (/parietal) cortices, we investigated the hypothesis that athletes with ongoing symptoms after […]
Methods of humane killing of laboratory fish: FELASA Working Group recommendations
As commissioned by the Federation of European Laboratory Animal Science Associations, these working group recommendations define the requirements to achieve the humane killing of fish, compare methods of killing, recommend methods of killing depending on context, and detail protocols leading to good practice. With a review of current practices in a fish laboratory and available […]
Exercise-Induced Symptom Exacerbation and Adverse Events in Moderate-to-Severe Traumatic Brain Injury
CONCLUSIONS: CRF and HLM exertional testing in the early subacute phase of recovery following moderate-to-severe TBI appears to be safe, with low rates of symptom exacerbation and adverse events identified.