Tag:

neurons

Dementia
Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Pathological Roles of Tmem106b in Neurodegeneration The involvement of TMEM106B in neurodegenerative diseases is a …

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Dementia
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis

by myneuronews August 7, 2025

by myneuronews August 7, 2025

Study Overview The research aimed to investigate the role of TDP-43 accumulation in the progression …

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Traumatic brain injury
Living in the Shadows: My Personal Perspective With Mental Health After a Concussion

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Understanding Concussions Concussions are a type of traumatic brain injury (TBI) that occur when a …

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Functional neurological disorders
AAV-based gene therapy ameliorates neurological deficits in a mouse model of childhood-onset neurodegeneration with cerebellar atrophy (CONDCA)

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Study Summary The study investigates the efficacy of adeno-associated virus (AAV)-based gene therapy in a …

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Dementia
Living and dying with Brenda Walker (and Motor Neurone Disease)

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Brenda’s Journey Brenda Walker’s experience with Motor Neurone Disease (MND) serves as a poignant narrative …

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Functional neurological disorders
Spreading depolarisation (SD): a potential underlying mechanism in functional neurological disorder (FND)

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Potential Mechanisms of Spreading Depolarisation Spreading depolarization (SD) refers to a wave of electrical change …

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Functional neurological disorders
Spreading depolarisation (SD): a potential underlying mechanism in functional neurological disorder (FND)

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Mechanisms of Spreading Depolarisation Spreading depolarisation (SD) is a complex physiological phenomenon that involves a …

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Functional neurological disorders
Hyperuniform Networks of Active Magnetic Robotic Spinners

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Network Characteristics of Magnetic Spinners The study of active magnetic robotic spinners offers fascinating insights …

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Functional neurological disorders
Impaired online and enhanced offline motor sequence learning in individuals with Parkinson’s disease

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Motor Sequence Learning in Parkinson’s Disease Motor sequence learning is fundamental to developing smooth and …

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Traumatic brain injury
Three-Month Durability of Bilateral Two-Level Stellate Ganglion Blocks for Traumatic Brain Injury: A Retrospective Analysis

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Study Overview The research investigates the effectiveness of bilateral two-level stellate ganglion blocks (SGB) in …

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Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury
Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are […]
Cognitive Proficiency after Traumatic Brain Injury in Children
Fifty-five children and adolescents with complicated mild-severe traumatic brain injury (TBI) completed the Wechsler Intelligence Scale for Children-Fifth Edition (WISC-V; Wechsler, 2014) within 1 to 12 months post-injury. Compared with demographically matched neurologically healthy controls, selected from the WISC-V standardization sample, participants with TBI demonstrated statistically significantly lower scores across WISC-V indices. The working memory, […]
Implementing Goal Attainment Scaling as a Person-Centered Measurement Tool to Direct Care and Evaluate Outcomes in Neurorehabilitation Settings
The purpose of this Special Communication is to describe barriers and facilitators to implementing goal attainment scaling (GAS) as a patient-centered measurement tool in neurorehabilitation settings. The experiences of three distinct neurorehabilitation settings that implemented GAS to enhance person-centered care and measure person-centered goal attainment are described: a neurorehabilitation service at an inpatient rehabilitation facility; […]
Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]