Tag:

neurons

Headaches
State-of-the-art preclinical techniques to study the impact of spreading depolarizations in awake rodents

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Overview of Spreading Depolarizations Spreading depolarizations (SDs) refer to a wave of electrical activity that …

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Traumatic brain injury
The Effect of Intracellular Calcium Buffer Bapta on Epileptiform Activity of Hippocampal Neurons

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview The investigation focuses on the role of intracellular calcium buffering in modulating epileptiform …

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Traumatic brain injury
The Effect of Intracellular Calcium Buffer Bapta on Epileptiform Activity of Hippocampal Neurons

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview The primary objective of this study was to investigate the role of Bapta, …

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Functional neurological disorders
Migraine and functional neurological disorder (FND)-a review of comorbidity and potential overlap

by myneuronews August 13, 2025

by myneuronews August 13, 2025

Comorbidities in Migraine and FND Migraine and Functional Neurological Disorder (FND) are both complex conditions …

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Dementia
Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Pathological Roles of Tmem106b in Neurodegeneration The involvement of TMEM106B in neurodegenerative diseases is a …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes During Glial Scar Formation After a traumatic brain injury (TBI), the brain undergoes …

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Dementia
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis

by myneuronews August 7, 2025

by myneuronews August 7, 2025

Study Overview The research aimed to investigate the role of TDP-43 accumulation in the progression …

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Functional neurological disorders
AAV-based gene therapy ameliorates neurological deficits in a mouse model of childhood-onset neurodegeneration with cerebellar atrophy (CONDCA)

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Study Summary The study investigates the efficacy of adeno-associated virus (AAV)-based gene therapy in a …

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Dementia
Living and dying with Brenda Walker (and Motor Neurone Disease)

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Brenda’s Journey Brenda Walker’s experience with Motor Neurone Disease (MND) serves as a poignant narrative …

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Traumatic brain injury
Living in the Shadows: My Personal Perspective With Mental Health After a Concussion

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Understanding Concussions Concussions are a type of traumatic brain injury (TBI) that occur when a …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Mild traumatic brain injury and concussion and persisting post-concussion symptoms: new guidelines to support evidence-based assessment and management in Australia and Aotearoa New Zealand
No abstract
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) can result in persistent cognitive deficits (particularly in attention, processing speed, and working memory), even years after the injury. The majority of behavioural studies have focussed on averaged cognitive performance scores, such as average reaction time or accuracy scores after mTBI. However, less is understood about how mTBI affects intraindividual […]
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
BACKGROUND: Traumatic brain injury (TBI) is one of the most important pediatric conditions worldwide. In Germany, hospitalization rates for mild TBI drastically exceed hospitalization rates from similar healthcare systems.
A Modified Repetitive Closed Head Injury Model Inducing Persistent Neuroinflammation and Functional Deficits Without Extensive Cortical Tissue Destruction
Traumatic brain injury (TBI) remains a significant clinical challenge, with limited treatment options and long-term neurological impairments. Mild to moderate TBI represents the most common form, making it a critical therapeutic target. However, current animal models poorly reflect human TBI pathophysiology, necessitating improved preclinical paradigms. Here, we present a refined repetitive closed head injury (rCHI) […]
Traumatic Microbleeds in Mild Traumatic Brain Injury: Stability, Distribution, and Association with Other Injuries
This study aimed to investigate whether the amount of traumatic microbleeds (TMBs) detected on magnetic resonance imaging (MRI) changes in different brain regions after a 3-month follow-up in adult patients with mild traumatic brain injury (mTBI). A 3 T MRI of the brain was conducted at baseline (3-17 days after trauma) and at 3 months […]