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NfL

Traumatic brain injury
Neuronal and Glial Biomarkers in Urine of Athletes with Different Risks of Head Trauma to Monitor Sports-Related Concussions

by myneuronews December 19, 2025

by myneuronews December 19, 2025

Biomarkers in Sports-Related Concussions Sports-related concussions (SRC) represent a significant public health concern, particularly among …

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Traumatic brain injury
Neuronal and Glial Biomarkers in Urine of Athletes with Different Risks of Head Trauma to Monitor Sports-Related Concussions

by myneuronews December 19, 2025

by myneuronews December 19, 2025

Biomarkers in Urine The detection of biomarkers in urine has emerged as a promising method …

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Traumatic brain injury
Plasma and Imaging Biomarker Changes Following Rotational and Contusional Models of Traumatic Brain Injury in Adolescent Pigs

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Study Overview This research investigates the biochemical and imaging alterations resulting from two distinct forms …

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Dementia
Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview The study investigated the changes in specific biomarkers in the blood of patients …

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Traumatic brain injury
Changes in peripheral blood and cognitive performance after nonconcussive head impacts in elite female soccer players

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Study Overview The research investigates the effects of nonconcussive head impacts on both the peripheral …

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Traumatic brain injury
IL6 in Combination with Either NfL, NTproBNP, or GFAP to Safely Discharge Children with Mild Traumatic Brain Injury

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Background and Rationale The investigation into the role of interleukin-6 (IL-6) in conjunction with biomarkers …

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Traumatic brain injury
Association of Preinjury Beta-Blocker Exposure With Brain Injury Biomarkers Following Traumatic Brain Injury

by myneuronews September 30, 2025

by myneuronews September 30, 2025

Study Overview This study investigates the connection between preinjury exposure to beta-blockers and the levels …

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Traumatic brain injury
Neurogranin as a Synaptic Biomarker in Mild Traumatic Brain Injury: A Systematic Review of Diagnostic and Pathophysiological Evidence

by myneuronews September 22, 2025

by myneuronews September 22, 2025

Neurogranin as a Biomarker Neurogranin is a neuronal protein that has garnered attention as a …

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Traumatic brain injury
Blood Biomarkers as Optimization Tools for Computed Tomography in Mild Traumatic Brain Injury Management in Emergency Departments: A Systematic Review

by myneuronews August 27, 2025

by myneuronews August 27, 2025

Blood Biomarkers and Their Role Blood biomarkers are measurable substances in the blood that can …

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Traumatic brain injury
An Analysis of Guardian Cap Use and Changes in the Concussion Rate in National Football League Preseason Practices From 2018 to 2023

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Guardian Cap Usage Trends The use of Guardian Caps in National Football League (NFL) preseason …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Multimodal Canonical Correlation Analysis with Joint Independent Component Analysis (mCCA+jICA) of IVIM and ASL MRI Reveals Perfusion and Diffusion Abnormalities in mTBI-A Pilot Study
Mild traumatic brain injury (mTBI) frequently causes subtle brain changes that are difficult to detect with conventional diagnostic approaches. In this exploratory pilot study, we combined tri-exponential intravoxel incoherent motion (IVIM) and pseudocontinuous arterial spin labeling (pCASL) MRI with Multimodal Canonical Correlation Analysis and joint independent component analysis (mCCA+jICA) to identify imaging signatures distinguishing mTBI […]