Diagnostic and Prognostic Significance of the S100 Biomarker in Blast-related Closed Traumatic Brain Injury
Background of S100 Biomarker The S100 protein family is a group of low molecular weight proteins primarily found in the […]
Long-term outcomes of hyperadrenergic orthostatic hypotension
Long-term Prognosis Hyperadrenergic orthostatic hypotension is a condition characterized by a significant drop in blood pressure upon standing, often accompanied
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Rituximab and IVIG added to plasma exchange improves the outcome of severe CNS demyelinating attacks: a retrospective study
Study Overview The study aimed to evaluate the effectiveness of combining rituximab and intravenous immunoglobulin (IVIG) therapy alongside plasma exchange
Mechanistic insights from experimental autoimmune encephalomyelitis into immune regulation, autophagy, gut microbiota, blood-brain barrier integrity, and NLRP3 inflammasome-mediated pyroptosis in multiple sclerosis: potential clinical implications
Mechanistic Insights into Multiple Sclerosis Multiple sclerosis (MS) is characterized by an autoimmune response that targets the central nervous system,
Immunoregulatory Effect of Curcumin on Experimental Autoimmune Encephalomyelitis (EAE), an Animal Model of Multiple Sclerosis (MS)
Overview of Curcumin’s Effects Curcumin, the active compound derived from the turmeric plant, has garnered significant attention in the scientific
Reading Comprehension and Employment After Traumatic Brain Injury: Preliminary Findings From Clinical Practice
Understanding Reading Comprehension After TBI Traumatic brain injury (TBI) can significantly impact various cognitive functions, and one area of concern
Epidemiology of traumatic brain injury in a South African major trauma cohort
Traumatic Brain Injury Patterns Traumatic brain injury (TBI) presents in various patterns that significantly influence patient management and outcomes. Understanding
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ISG15/ISGylation in central nervous system diseases: molecular mechanisms and therapeutic targeting
Mechanisms of ISG15/ISGylation ISG15, or Interferon-Stimulated Gene 15, plays a crucial role in the immune response and cellular mechanisms, particularly
Rituximab and IVIG added to plasma exchange improves the outcome of severe CNS demyelinating attacks: a retrospective study
Study Overview This retrospective study examines the effectiveness of combining rituximab and intravenous immunoglobulin (IVIG) with plasma exchange in treating
Investigations of remibrutinib in models pertinent to multiple sclerosis
Study Overview The investigation focused on remibrutinib, a selective Bruton’s tyrosine kinase (BTK) inhibitor, and its potential applications in treating
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