Tag:

patient outcomes

Functional neurological disorders
Expanding the spectrum of ATP8A2 mutations: a new splicing variant and systematic review of CAMRQ4 syndrome

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Overview of ATP8A2 and CAMRQ4 Syndrome ATP8A2 is a gene that encodes a protein crucial …

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Functional neurological disorders
Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Activity-Dependent Degradation of Kv4.2 The study investigates the protein Kv4.2, a key player in the …

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Traumatic brain injury
Clinical Characteristics and Outcomes of Pediatric Traumatic Brain Injury Patients in a Tertiary Regional Trauma Center in the Philippines

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Patient Demographics and Injury Mechanisms The study cohort comprised pediatric patients who sustained traumatic brain …

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Traumatic brain injury
Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Study Overview This study explores the effectiveness of hybrid membrane-coated cyclosporine A (CsA) nanocrystals in …

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Functional neurological disorders
Autoimmune psychosis: Psychopathological patterns and outcome after immunotherapy

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Autoimmune Psychosis Overview Autoimmune psychosis is an emerging area of interest in neurology and psychiatry, …

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Functional neurological disorders
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Microglia Replacement Strategy The study introduces an innovative approach to addressing neurological disorders through the …

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Functional neurological disorders
Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Mechanisms of Ligamentum Flavum Hypertrophy The study delves into the complex changes that occur in …

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Dementia
Association of Alzheimer’s Disease and Related Dementias (ADRD) With Days at Home Among Medicare Beneficiaries After a Heart Failure Hospitalization

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Association With Days at Home The amount of time spent at home after a hospitalization …

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Movement Disorders
Tics and Parkinson’s Disease: Clinical and Pathophysiological Insights from a Rare Syndromic Association

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Understanding Tics in Parkinson’s Disease Tics are sudden, repetitive movements or vocalizations that can occur …

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Traumatic brain injury
Use of physical exertion to enhance objective testing following mild traumatic brain injury: a systematic review

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Physical Exertion as a Rehabilitation Strategy Physical exertion has gained recognition as a potential rehabilitative …

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Traumatic brain injury graphing: A case study of Charles Whitman
Research has identified violent behavior (i.e., assault, murder, and suicide) as a possible sequela of moderate to severe traumatic brain injury (TBI) and repeated mild TBI (rmTBI). However, misconceptions about consciousness and its ability to control an injured brain, the diverse spectrum of potential outcomes, and the role genetics/environmental factors can play make proving TBI's […]
Injury Prevention Programs in Youth Football: A Narrative Review of the FIFA 11+ and FUNBALL Programs
Football (soccer) is a dynamic sport popular among youth, but it poses risks of injuries such as ligament tears, fractures, and concussions. Injury prevention programs are essential for safeguarding young athletes' health and performance. This review evaluates two key programs: the 11+ and FUNBALL. The 11+ program is a structured warm-up designed for young female […]
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory
Every time a person sustains a blow to the head, they receive multiple atypical sensory inputs, often including pain. These directly stimulate the central nervous system. Yet, sensory input as a causal agent of neurophysiological dysfunction and post-concussion symptoms has never been explored. A new theory is proposed of sensory driven neurophysiological mechanisms of concussion […]
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury
Although tumor necrosis factor-alpha (TNF-α) plays an important role in the development of obsessive-compulsive disorder (OCD), the pathogenesis remains unclear. Since transient receptor potential melastatin 3 (TRPM3) channels are activated during inflammatory conditions, crosstalk with TNF-α in the progression of OCD has not been investigated yet. We hypothesize that mild traumatic brain injury (mTBI) stimulates […]
Age-Adjusted Cut-Off Values for Glial Fibrillary Acidic Protein and Ubiquitin Carboxy-Terminal Hydrolase L1 Improve the Diagnostic Accuracy of the Abbott Mild Traumatic Brain Injury Assay
Objectives: To establish age-adjusted cut-off values for glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and assess their impact on the diagnostic performance of the mild traumatic brain injury (mTBI) assay. Methods: The study included 175 adult mTBI patients presenting at the emergency department (ED) within 12 h from head trauma in […]