Tag:

personalized medicine

Movement Disorders
Evaluating the Homogeneity of the PSP-RS Syndrome beyond Core Features

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Evaluate the Homogeneity of PSP-RS Syndrome The Progressive Supranuclear Palsy-Richardson Syndrome (PSP-RS) represents a specific …

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Headaches
Raising the bar in migraine prevention: Toward freedom and optimal control

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Current Approaches to Migraine Prevention Migraine prevention encompasses a variety of methodologies aimed at reducing …

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Functional neurological disorders
Whole-exome sequencing identifies 5 novel genes associated with carpal tunnel syndrome

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Whole-exome sequencing methodology Whole-exome sequencing (WES) is a powerful genomic tool that has enabled researchers …

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Functional neurological disorders
Unveiling diverse clinical symptom patterns and neural activity profiles in major depressive disorder subtypes

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Symptom Patterns in Major Depressive Disorder In the realm of mental health, Major Depressive …

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Functional neurological disorders
Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Understanding Mild Cognitive Impairment Heterogeneity Mild cognitive impairment (MCI) is a clinical condition that marks …

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Functional neurological disorders
In-silico analysis of deleterious non-synonymous SNPs in the human AVPR1a gene linked to autism

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Significance of AVPR1a Gene in Autism The AVPR1a gene, which encodes the arginine vasopressin receptor …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apoc1 with Alzheimer’s Disease Recent research has underscored the significance of the apolipoprotein …

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Functional neurological disorders
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Mechanisms of DG9 Action DG9 has emerged as a pivotal compound in the realm of …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF in Depression Brain-Derived Neurotrophic Factor (BDNF) is a crucial protein that supports the …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF’s Role in Depression Brain-derived neurotrophic factor (BDNF) is a protein that plays a …

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Reviewer Comment on Li et al.: “Systematic review: mental health outcomes in Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy”
Mental Health Outcomes Mental health outcomes in individuals diagnosed with Guillain-Barré syndrome (GBS) and chronic…
Quinine Sulfate for Muscle Cramps in Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind Crossover Trial
Study Overview The study conducted a randomized, double-blind crossover trial to evaluate the effectiveness of…
The Role of Left Atrial Strain in Differentiating Embolic Stroke of Undetermined Source From Other Acute Ischemic Stroke Subtypes Related to Large-Vessel Occlusion
Background and Significance The study of left atrial strain has emerged as a crucial component…
Raising the bar in migraine prevention: Toward freedom and optimal control
Current Approaches to Migraine Prevention Migraine prevention encompasses a variety of methodologies aimed at reducing…
Evaluating the Homogeneity of the PSP-RS Syndrome beyond Core Features
Evaluate the Homogeneity of PSP-RS Syndrome The Progressive Supranuclear Palsy-Richardson Syndrome (PSP-RS) represents a specific…

Somatic Symptom Disorder After Mild Traumatic Brain Injury
CONCLUSIONS: SSD after mTBI is associated with an increased burden of symptoms, comorbidity, and disability. Early identification of at-risk patients appears feasible. SSD may be a useful framework for conceptualizing poor outcome from mTBI in patients with prominent psychological distress and guiding rehabilitation.
The Relationship Between Sex, Fatigue, and Post-Concussion Symptoms Differs Between Those With Mild Traumatic Brain Injury Versus Trauma Control and Healthy Control Participants
CONCLUSIONS: This study indicates that the vulnerability of females to report elevated PCS in the post-acute period after traumatic injury is specific to those who have incurred a concomitant mTBI. Further, only some subcomponents of fatigue independently explain variance in PCS reporting, with the groups showing variability in these associations. Further work is needed to […]
Patient-Reported Outcomes Measurement Information System (PROMIS) outcomes: Higher odds of adverse mental health when physical function is impaired
PurposeBalance and vestibular disorders have a profound impact on quality of life. Anxiety (ANX) and depression (DEP) are common with dizziness, vertigo, or imbalance. It is unclear whether self-reported anxiety or depression depends on perceived physical function for individuals participating in vestibular rehabilitation (VPT). We hypothesized that individuals with worse physical function would be more […]
Psychiatric outcomes after mild concussion by treatment timing and age
Previous guidance for mild concussion treatment has recommended physical and cognitive rest. However, it remains unknown if patients who received treatment at different times had differential neuropsychiatric outcomes. We examined if patients who received immediate treatment less than one week after a mild concussion had a different risk for subsequent depression or anxiety compared with […]
Modelling and Standardisation of EHR Data for Mild Traumatic Brain Injury Patient Management
In Spain, traumatic brain injury (TBI) affects 200 new cases per 100,000 inhabitants, making it a significant cause of morbidity and mortality globally and a frequent reason for emergency department attention. This study addresses the lack of consensus on the use of diagnostic tests to exclude intracranial lesions, leading to overuse of Computed Tomography (CT) […]