Tag:

personalized medicine

Traumatic brain injury
Knockout of indoleamine 2,3-dioxygenase 1 gene expression improves depressive and anxiety-like phenotypes in a murine model of mild traumatic brain injury

by myneuronews August 3, 2025

by myneuronews August 3, 2025

Study Overview The research investigates the effects of knocking out the expression of the indoleamine …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
The adjunct role of pharmacotherapy in multimodal treatment of paediatric functional neurological disorder

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) represents a complex spectrum of symptoms …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder in patients and cell line models

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Pantethine Effects on Cardiomyopathy Pantethine, a derivative of vitamin B5, has recently garnered attention for …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Re-evaluating albumin use in traumatic brain injury

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Albumin Use in Traumatic Brain Injury The role of albumin in the management of traumatic …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Biofilm Formation of Pseudomonas aeruginosa in Cystic Fibrosis: Mechanisms of Persistence, Adaptation, and Pathogenesis

by myneuronews July 30, 2025

by myneuronews July 30, 2025

Biofilm Structure and Composition The biofilm formed by Pseudomonas aeruginosa is a complex, multi-layered structure …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Expanding the Phenotypic Spectrum Associated with DPH5-Related Diphthamide Deficiency

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Phenotypic Spectrum of DPH5 Deficiency DPH5 deficiency is a rare genetic condition that impacts the …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Neural Network Classification of Barnes Maze Search Strategy Utilization

by myneuronews July 28, 2025

by myneuronews July 28, 2025

Study Overview This research focuses on the application of neural network techniques to classify the …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
GSAformer: Group sparse attention transformer for functional brain network analysis

by myneuronews July 27, 2025

by myneuronews July 27, 2025

Methodology Overview The study introduced GSAformer, a novel model designed to improve the analysis of …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Gut microbiota and myelination: Crosstalk across the lifespan and microbiota-based modulation strategies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Gut Microbiota’s Role in Myelination The gut microbiota, a complex community of microorganisms residing in …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

Read more

0 Facebook Twitter Pinterest Email

Spontaneous Regression of Cranial Vault Lymphoma: A Case Report
Case Presentation A 54-year-old male patient, previously healthy with no notable medical history, presented with…
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis
Study Overview The research aimed to investigate the role of TDP-43 accumulation in the progression…
Reframing Functional Neurological Disorders in Modern Medicine
Reframing the Understanding of FND Functional Neurological Disorder (FND) represents a complex interplay of neurological…
Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design
Study Summary This study focused on evaluating the effectiveness of inpatient cognitive analytic therapy (CAT)…
Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT
Study Summary The Physio4FMD randomized controlled trial aimed to evaluate the effectiveness of specialist physiotherapy…

Youth Ages 4 to 13 Trends of Sports Concussions With Loss of Consciousness From 2014-2023 National Electronic Injury Surveillance System
CONCLUSION: The results of this study show a decrease in the overall level of LOC incidence in US youth athletes ages 4 to 13 years from 2014 to 2023 across 8 sports. The data delineate from previous studies that show an exponential increase in LOC incidence; however, the underlying reasons are still unclear and warrant […]
Development of the Common Cognitive Complaints after Concussion (C4) questionnaire: a treatment-planning tool for military service members and veterans with mild traumatic brain injury
CONCLUSION: The C4 adequately captured activity-level functional impairments common to mTBI, and clinicians endorsed its utility as a useful tool to personalize treatment targets.
Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]
Tackle characteristics associated with concussion in elite men's rugby union: unpicking the differences between tacklers and ball-carriers
CONCLUSIONS: Lower tackles reduce the chances of concussion to ball-carriers. The influence of tackle height on concussion to tacklers is more nuanced, but the chances are relatively low when contact is made with the ball-carrier's torso. These findings support ongoing implementation of strategies to reduce concussion risk by lowering tackle height to target the torso.