Tag:

personalized medicine

Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Biomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Design and Population The study utilized a robust multisite, multiancestry design, involving a comprehensive …

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Traumatic brain injury
N-Formylmethionine Is a Biologically Active Diagnostic Marker of Mild Traumatic Brain Injury

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview This research investigates the role of N-Formylmethionine (fMet) as a potential biomarker for …

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Functional neurological disorders
Enhancing diagnostic yield in functional seizures: A narrative review, design and implementation of a novel ictal testing battery for video telemetry

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Enhancing Diagnostic Approaches The landscape of diagnosing functional seizures has evolved significantly, driven by a …

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Functional neurological disorders
Enhancing diagnostic yield in functional seizures: A narrative review, design and implementation of a novel ictal testing battery for video telemetry

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Enhancing Diagnostic Yield The complex nature of functional seizures, often characterized by a mismatch between …

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Functional neurological disorders
Modulating the sense of agency in functional neurological disorder using real-time fMRI neurofeedback: a proof-of-concept study

by myneuronews November 6, 2025

by myneuronews November 6, 2025

Modulation of Sense of Agency The concept of the sense of agency refers to the …

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Headaches
Unexpected genomic architecture in a sporadic case of C1-INH Hereditary Angioedema: the hidden heritability

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Genomic Architecture Insights The genomic architecture in individuals with C1-INH Hereditary Angioedema (HAE) showcases a …

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Traumatic brain injury
Can symptom-severity phenotypes identify depression risk after mild traumatic brain injury? A cluster-based approach

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Overview This research investigates the relationship between symptom severity phenotypes and the risk of …

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Traumatic brain injury
Mobile Health App for Adults with Persisting Postconcussion Symptoms: Development and Usability Study

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Overview The development of a mobile health application aimed at supporting adults suffering from …

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Profiles of cold executive function performance among pediatric acquired brain injury
CONCLUSIONS: Distinct executive function profiles were observed across ABI subtypes, with PAS associated with the most pervasive impairments, TBI with selective deficits, and BT with targeted planning difficulties. These findings highlight the importance of tailored cognitive rehabilitation strategies based on ABI subtype.
Longitudinal neurocognitive outcomes in children with mild traumatic brain injury: An ABCD cohort analysis
CONCLUSIONS: The findings highlight the importance of accounting for pre-injury differences when evaluating neurocognitive outcomes following pediatric mTBI. Neurocognitive differences within a year post-injury may be more related to pre-existing individual factors rather than the injury itself, underscoring the need for a comprehensive approach in studying pediatric mTBI.
Fear Avoidance after Concussion Tool (FACT): patient-reported outcome measure development and content validation
CONCLUSION: The FACT has been developed to evaluate fear avoidance behaviour following concussion and has content validity. Future research should evaluate other measurement properties before implementation.
Spare the brain: female football players' perspectives of heading the ball, concussion knowledge and attitudes. A qualitative study
The aim of this study was to explore female football (soccer) players' perspectives of heading the ball, and perceived header injury risk. A qualitative approach was undertaken using reflexive thematic analysis. Focus groups and individual interviews were conducted using a semi-structured interview guide. Participants also completed a survey containing a validated concussion knowledge and attitudes […]
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
Traumatic brain injury (TBI) constitutes a major global public health concern associated with substantial mortality and long-term disability, while its diagnostic approaches and underlying pathophysiological mechanisms remain to be fully elucidated. In this study, we conducted longitudinal metabolomic profiling of cerebrospinal fluid (CSF) from 23 TBI patients (9 mild, 14 severe) and 5 uninjured controls […]