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personalized treatment

Functional neurological disorders
Tailored provocation in functional seizures, a pilot study

by myneuronews November 16, 2025

by myneuronews November 16, 2025

Study Objectives The pilot study aimed to explore the efficacy of tailored provocation for eliciting …

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Functional neurological disorders
Symptom modelling using hypnosis

by myneuronews November 16, 2025

by myneuronews November 16, 2025

Symptom Modelling Framework The symptom modelling framework developed in the context of hypnosis provides a …

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Traumatic brain injury
Fear Avoidance after Concussion Tool (FACT): patient-reported outcome measure development and content validation

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The development of the Fear Avoidance after Concussion Tool (FACT) was initiated to …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Summary The study investigates the genetic underpinnings of Functional Seizure Disorder (FSD), a condition …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Design and Population The study utilized a robust multisite, multiancestry design, involving a comprehensive …

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Traumatic brain injury
Objective Markers for Diagnosing Concussions: Beyond Blood Biomarkers and the Role of Real-Time Diagnostic Tools

by myneuronews November 13, 2025

by myneuronews November 13, 2025

Diagnostic Innovations Recent advancements in concussion diagnostics have shown promise in enhancing the speed and …

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Functional neurological disorders
Phenotyping Functional Gait Disorder: An Exploratory Analysis of Existing Frameworks

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Phenotyping Functional Gait Disorder Functional Gait Disorder (FGD) is increasingly recognized as a complex presentation …

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Functional neurological disorders
Diagnosis and treatment of functional visual disorder

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Overview of Functional Visual Disorder Functional Visual Disorder (FVD) represents a complex and multifaceted condition …

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Functional neurological disorders
Phenotyping Functional Gait Disorder: An Exploratory Analysis of Existing Frameworks

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Understanding Functional Gait Disorder Functional Gait Disorder (FGD) presents a unique challenge in clinical neurology, …

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Traumatic brain injury
Chronic Traumatic Encephalopathy Neuropathologic Change in Military Veterans

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic Traumatic Encephalopathy (CTE) is a degenerative brain disease commonly …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]