Tag:

personalized treatment

Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Headaches
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in …

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Functional neurological disorders
Changes of functional brain network topology associated with nutritional indicator of patients with recurrent major depressive disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Functional Brain Network Changes Recent studies have highlighted intriguing transformations in the topology of functional …

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Functional neurological disorders
Biopsychosocial prognostic indicators in Functional Neurological Disorder: A systematic review

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Prognostic Factors in Functional Neurological Disorder Understanding the prognostic factors associated with Functional Neurological Disorder …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Movement Disorders
Distinct 11C-ER176 PET Neuroinflammatory Profiles and Tau Colocalization in Progressive Apraxia of Speech With and Without Parkinson-plus Syndrome

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The research focuses on the complex relationship between neuroinflammation and tau pathology in …

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Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Functional neurological disorders
Functional Syndromes in the Pediatric Population and Their Rehabilitation Management: Chronic Pain Syndrome and Functional Neurologic Disorder

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Understanding Functional Syndromes Functional syndromes encompass a range of medical conditions where psychological or neurological …

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The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury
CONCLUSION: HRV can be used as an independent predictor of unfavorable prognosis in patients with TBI. Including the SDNN index in prognostic models helps to effectively predict the prognosis of adult patients with TBI.
Reply: Concussions Are Associated With Increases in Blood Pressure and Cardiovascular Risk in American-Style Football Athletes
No abstract
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head
CONCLUSIONS: Plasma and salivary S100B levels effectively discriminate mild from severe TBI, complementing current clinical severity scales. Their use may support rapid decision-making in emergency departments, especially given the simplicity, non-invasiveness, and feasibility of salivary sampling. These findings support integrating S100B measurement into TBI management protocols to enhance clinical accuracy and patient outcomes.
Letter to the Editor: The importance of using validated case definitions in the epidemiology of concussion
No abstract
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D corticomimetic in vitro model of concussion was developed, confirming aldehyde production following impact. Total aldehyde levels were […]