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personalized treatment

Traumatic brain injury
The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Predictive Value of Heart Rate Variability Heart rate variability (HRV) refers to the fluctuations in …

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Functional neurological disorders
Changes of functional brain network topology associated with nutritional indicator of patients with recurrent major depressive disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Functional Brain Network Changes Recent studies have highlighted intriguing transformations in the topology of functional …

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Headaches
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in …

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Functional neurological disorders
Biopsychosocial prognostic indicators in Functional Neurological Disorder: A systematic review

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Prognostic Factors in Functional Neurological Disorder Understanding the prognostic factors associated with Functional Neurological Disorder …

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Functional neurological disorders
Abnormal static and dynamic regional homogeneity in adolescent major depressive disorder with somatic symptoms: a resting-state fMRI study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Methodological Overview The study employs a resting-state functional magnetic resonance imaging (fMRI) approach to examine …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Functional neurological disorders
Functional Syndromes in the Pediatric Population and Their Rehabilitation Management: Chronic Pain Syndrome and Functional Neurologic Disorder

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Understanding Functional Syndromes Functional syndromes encompass a range of medical conditions where psychological or neurological …

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Acute effects of sport-related concussion among adolescents with a self-reported history of treatment for anxiety or depression
Objective: This study compared symptom reporting and cognitive test performance within 72 h of a suspected concussion between high school student-athletes with and without pre-injury self-reported mental health treatment. Methods: Eight hundred seventy-nine high school athletes with (n = 75) and without (n = 804) a self-reported history of treatment for anxiety or depression underwent […]
Boston University Alzheimer's Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer's disease and related dementias
We describe the rationale, methodology, and design of the Boston University Alzheimer's Disease Research Center (BU ADRC) Clinical Core (CC). The CC characterizes a longitudinal cohort of participants with/without brain trauma to characterize the clinical presentation, biomarker profiles, and risk factors of post-traumatic Alzheimer's disease (AD) and AD-related dementias (ADRD), including chronic traumatic encephalopathy (CTE). […]
Sensory processing patterns in pediatric mild traumatic brain injury: A longitudinal study
Sensory processing (SP) difficulties, such as heightened sensitivity to sensory input, have been linked to prolonged recovery and persistent post-concussive symptoms in adults following mild traumatic brain injury (mTBI). However, research on SP across different sensory inputs after pediatric mTBI is limited. This study examined SP patterns in children and adolescents aged 6-17 years with […]
Effects of Lifetime Exposure to Sports-Related Head Impacts on Brain Injury and Inflammatory Blood Biomarkers Among Former Middle-Aged Athletes
Repetitive head impacts from contact sports are associated with an increased risk of neurodegenerative conditions. While studies have examined acute and chronic outcomes in young and deceased athletes, research on middle-aged former athletes remains limited. We employed multiplex biomarker approaches to examine whether brain injury and systemic inflammatory blood biomarkers are reflective of ≥10 years […]
Pain Management Strategies and Adverse Effects of Opioids in Patients with Neurotrauma with Acute and Chronic Pain
Pain is prevalent and a major source of disability after a traumatic brain injury (TBI) and a spinal cord injury (SCI). With a view of reducing the pain burden in neurotrauma, this study aimed to describe the use of pain management strategies and the adverse effects of opioids in patients with TBI and SCI. We […]