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personalized treatment

Functional neurological disorders
Modulating the sense of agency in functional neurological disorder using real-time fMRI neurofeedback: a proof-of-concept study

by myneuronews November 6, 2025

by myneuronews November 6, 2025

Neurofeedback Mechanism Neurofeedback is an innovative approach that leverages real-time brain activity data to help …

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Functional neurological disorders
Individualized psychotherapy reveals a very high prevalence of adverse life events in functional neurological disorders

by myneuronews November 5, 2025

by myneuronews November 5, 2025

High Prevalence of Adverse Life Events Recent research highlights a striking correlation between functional neurological …

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Functional neurological disorders
Pathophysiology of functional neurological disorder for the general neurologist

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Pathophysiological Mechanisms The pathophysiological mechanisms underlying functional neurological disorder (FND) are complex and multifaceted. Current …

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Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

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Functional neurological disorders
The Impact of Pregnancy on Functional Neurological Disorder (FND)

by myneuronews November 5, 2025

by myneuronews November 5, 2025

The Effects of Pregnancy on FND Symptoms Pregnancy can significantly influence the symptoms experienced by …

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Functional neurological disorders
Individualized psychotherapy reveals a very high prevalence of adverse life events in functional neurological disorders

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Prevalence of Adverse Life Events Recent findings indicate that individuals with functional neurological disorders (FND) …

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Functional neurological disorders
Pathophysiology of functional neurological disorder for the general neurologist

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Pathophysiological Mechanisms The pathophysiology of Functional Neurological Disorder (FND) encompasses a complex interplay of biological, …

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Functional neurological disorders
Pathophysiology of functional neurological disorder for the general neurologist

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a diverse array of neurological symptoms …

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Functional neurological disorders
Pathophysiology of functional neurological disorder for the general neurologist

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Pathophysiological Mechanisms The pathophysiology of functional neurological disorder (FND) is complex and multifaceted, reflecting an …

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Dementia
Cognitive performance in patients with ischemic stroke and additional myocardial injury – results from the multicenter prospective observational PRAISE study

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Cognitive outcomes in stroke patients Cognitive performance is a critical aspect of recovery after a …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]