Tag:

personalized treatment

Dementia
Developing biobanking processes for Alzheimer’s disease and related dementia research in Africa: Experience from the Recruitment and Retention for Alzheimer’s Disease Diversity in the Alzheimer’s Disease Sequencing Project (READD-ADSP)

by myneuronews August 17, 2025

by myneuronews August 17, 2025

Biobanking Challenges in Africa Establishing effective biobanking processes in Africa presents unique challenges that stem …

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Headaches
Interpretable Machine Learning Integrates Multi-Source Biomarkers for Osteoarthritis Diagnosis and Mechanistic Insights: A Temporomandibular Joint Model

by myneuronews August 16, 2025

by myneuronews August 16, 2025

Study Overview This research explores the integration of diverse biomarkers through interpretable machine learning techniques …

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Traumatic brain injury
Abnormal brain morphology and morphological brain network in adults with acute mild traumatic brain injury

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Abnormal Brain Morphology Acute mild traumatic brain injury (mTBI) can lead to observable alterations in …

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Traumatic brain injury
Context Matters: Influence of Injury Context on Long-Term Psychiatric and Cognitive Outcomes in Combat Veterans With Mild Traumatic Brain Injury History

by myneuronews August 13, 2025

by myneuronews August 13, 2025

Injury Context and Its Relevance The circumstances surrounding a mild traumatic brain injury (mTBI) can …

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Traumatic brain injury
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury

by myneuronews August 12, 2025

by myneuronews August 12, 2025

Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the …

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Traumatic brain injury
Clinical outcomes and quality of life after endovascular embolization for vein of Galen aneurysmal malformation (VGAM): a study from a low-and middle-income country

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Study Overview The study focuses on the clinical outcomes and implications for quality of life …

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Dementia
Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Pathological Roles of Tmem106b in Neurodegeneration The involvement of TMEM106B in neurodegenerative diseases is a …

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Traumatic brain injury
Biological Markers of Brain Network Connectivity and Pain Sensitivity Distinguish Low Coping from High Coping Veterans with Persistent Post-Traumatic Headache

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Biological Markers and Connectivity Recent advances in neuroimaging and biomolecular research have enhanced our understanding …

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Traumatic brain injury
Letter: Mild Traumatic Brain Injury in Older Adults: Recovery Course and Insights on Early Predictors of Outcome

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Recovery Patterns in Older Adults The recovery patterns following mild traumatic brain injury (mTBI) in …

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Headaches
Spontaneous Regression of Cranial Vault Lymphoma: A Case Report

by myneuronews August 7, 2025

by myneuronews August 7, 2025

Case Presentation A 54-year-old male patient, previously healthy with no notable medical history, presented with …

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National and subnational burden of neurological disorders in Iran, 1990 to 2021: results from the global burden of disease study 2021
Burden of Neurological Disorders in Iran The landscape of neurological disorders in Iran presents a…
Nuclear membrane disruption in neurodegenerative diseases: Emerging perspectives
Nuclear membrane function in neuronal health The nuclear membrane, or nuclear envelope, is a critical…
Cognitive impairment and altered structural connectivity after mild traumatic brain injury: A longitudinal study based on generalized q-sampling imaging
Cognitive Impairment Assessment The assessment of cognitive impairment following mild traumatic brain injury (mTBI) is…
Prevalence and Risk of Anxiety and Depression after Concussion: A TRANSCENDENT Study
Study Overview The investigation focused on the prevalence and risk factors associated with anxiety and…
Inhibition of p38 MAPK after repetitive mTBI ameliorates immune signaling and functional deficits
Study Overview This study investigates the effects of inhibiting p38 MAPK (mitogen-activated protein kinase) following…

NSAID Use Is Not Associated With Persisting Symptoms in Adolescent Concussion
CONCLUSIONS: In adolescents, NSAID use was associated with more severe symptoms but not PSaC. To optimize clinical guidance, future research should further evaluate the role of NSAIDs in concussion recovery.
Reduced cortical excitability is associated with head impact severity and cognitive symptoms in adolescent football players
American tackle football is associated with high rates of concussion, leading to neurophysiological disturbances and debilitating clinical symptoms, but previous investigations have largely ignored aperiodic neurophysiological activity. In this study, we use pre- and post-season resting-state magnetoencephalography (MEG) to examine whether concussion during a season of football is related to changes in neurophysiology and whether […]
Severity of physical, emotional, and cognitive symptoms is associated with future persistence of acute post-traumatic headache attributed to mild traumatic brain injury
AimPost-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) frequently co-occurs with other physical, cognitive, and emotional symptoms. This study assessed associations between PTH improvement and these symptoms in individuals with acute headaches (APTH) and compared symptoms between those who had recently developed persistent PTH (PPTH) to those who had long-standing PPTH.MethodsThis study included […]
Sex hormone dysregulation after traumatic brain injury: interactions with sleep disturbances and seizure susceptibility
Each year, approximately 2.9 million people in the United States sustain a traumatic brain injury (TBI), many of whom go on to experience chronic secondary complications such as post-traumatic epilepsy (PTE) and sleep-wake disturbances. These outcomes arise from complex secondary injury processes, including neuroinflammation, oxidative stress, and disruptions in neuroendocrine signaling. While inflammatory and excitotoxic […]
Systemic inflammation and its associations in acute moderate-severe Traumatic Brain Injury: a cross-sectional study
Traumatic Brain Injury (TBI) triggers an acute systemic inflammatory response, which may impact outcomes. This response may interact with pre-existing factors linked to inflammation, such as age, to influence outcomes. Previous studies have typically measured few cytokines, but high-dimensional proteomic approaches can sensitively detect a broad range of inflammatory markers, to better characterise post-TBI inflammation. […]