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personalized treatment

Headaches
Clinical characteristics and efficacy of intrathecal therapy in pediatric lupus encephalopathy

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Clinical Presentation and Diagnosis Pediatric lupus encephalopathy, often associated with systemic lupus erythematosus (SLE), manifests …

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Traumatic brain injury
Traumatic Venous Sinus Thrombosis: Patient and Practice Patterns at a Major Trauma Center

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Patient Characteristics The characteristics of patients diagnosed with traumatic venous sinus thrombosis reveal crucial insights …

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Traumatic brain injury
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Impact of Mild Traumatic Brain Injury Mild traumatic brain injury (mTBI) poses significant challenges not …

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Traumatic brain injury
Prevalence of low scores in the Uniform Data Set version 3.0: Comparison of older adults with and without a self-reported history of traumatic brain injury

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Study Overview This study investigates the occurrence of low scores within the Uniform Data Set …

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Traumatic brain injury
Neuroimaging Characterization of Acute Traumatic Brain Injury with Focus on Frontline Clinicians: Recommendations from the 2024 National Institute of Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Imaging Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Neuroimaging Techniques in Traumatic Brain Injury Neuroimaging plays a crucial role in the assessment and …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Traumatic brain injury
Optimal Diagnostic Strategies for Concussion-Related Vision Disorders: A Review

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Concussion-Related Vision Disorders Concussion-related vision disorders encompass a range of visual symptoms that can …

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Traumatic brain injury
The Relationship Between Sex, Fatigue, and Post-Concussion Symptoms Differs Between Those With Mild Traumatic Brain Injury Versus Trauma Control and Healthy Control Participants

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Study Overview In recent years, the complex interplay between sex, fatigue, and post-concussion symptoms has …

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Traumatic brain injury
Modelling and Standardisation of EHR Data for Mild Traumatic Brain Injury Patient Management

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Background and Rationale The landscape of healthcare has witnessed a rapid transformation with the advent …

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Headaches
Current Evidence in the Management of Central Skull Base Osteomyelitis: A Systematic Review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Study Overview Central Skull Base Osteomyelitis (CSBO) is a serious infection that affects the bony …

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National and subnational burden of neurological disorders in Iran, 1990 to 2021: results from the global burden of disease study 2021
Burden of Neurological Disorders in Iran The landscape of neurological disorders in Iran presents a…
Nuclear membrane disruption in neurodegenerative diseases: Emerging perspectives
Nuclear membrane function in neuronal health The nuclear membrane, or nuclear envelope, is a critical…
Cognitive impairment and altered structural connectivity after mild traumatic brain injury: A longitudinal study based on generalized q-sampling imaging
Cognitive Impairment Assessment The assessment of cognitive impairment following mild traumatic brain injury (mTBI) is…
Prevalence and Risk of Anxiety and Depression after Concussion: A TRANSCENDENT Study
Study Overview The investigation focused on the prevalence and risk factors associated with anxiety and…
Inhibition of p38 MAPK after repetitive mTBI ameliorates immune signaling and functional deficits
Study Overview This study investigates the effects of inhibiting p38 MAPK (mitogen-activated protein kinase) following…

Severity of physical, emotional, and cognitive symptoms is associated with future persistence of acute post-traumatic headache attributed to mild traumatic brain injury
AimPost-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) frequently co-occurs with other physical, cognitive, and emotional symptoms. This study assessed associations between PTH improvement and these symptoms in individuals with acute headaches (APTH) and compared symptoms between those who had recently developed persistent PTH (PPTH) to those who had long-standing PPTH.MethodsThis study included […]
NSAID Use Is Not Associated With Persisting Symptoms in Adolescent Concussion
CONCLUSIONS: In adolescents, NSAID use was associated with more severe symptoms but not PSaC. To optimize clinical guidance, future research should further evaluate the role of NSAIDs in concussion recovery.
Systemic inflammation and its associations in acute moderate-severe Traumatic Brain Injury: a cross-sectional study
Traumatic Brain Injury (TBI) triggers an acute systemic inflammatory response, which may impact outcomes. This response may interact with pre-existing factors linked to inflammation, such as age, to influence outcomes. Previous studies have typically measured few cytokines, but high-dimensional proteomic approaches can sensitively detect a broad range of inflammatory markers, to better characterise post-TBI inflammation. […]
Sex hormone dysregulation after traumatic brain injury: interactions with sleep disturbances and seizure susceptibility
Each year, approximately 2.9 million people in the United States sustain a traumatic brain injury (TBI), many of whom go on to experience chronic secondary complications such as post-traumatic epilepsy (PTE) and sleep-wake disturbances. These outcomes arise from complex secondary injury processes, including neuroinflammation, oxidative stress, and disruptions in neuroendocrine signaling. While inflammatory and excitotoxic […]
Structural brain differences in professional Australian rules footballers following mild traumatic brain injury: When head size matters
INTRODUCTION: Concussion, a type of mild traumatic brain injury common in collision sports, is thought to be associated with subtle brain changes that are not visually appreciable on conventional neuroimaging. This study quantified differences in subcortical volumes from structural MRI between 31 recently concussed professional Australian rules footballers (within 3 months of injury) and 37 […]