Harnessing Microglial Repopulation: From Inflammatory Drivers to Therapeutic Allies in CNS Diseases
Microglial Functions in CNS Health Microglia are the primary resident immune cells in the central nervous system (CNS), playing a […]
Challenges and Innovation for Diagnosing and Treatment of Secondary Progressive Multiple Sclerosis
Challenges in Diagnosis Diagnosing secondary progressive multiple sclerosis (SPMS) presents a multitude of challenges, primarily due to the complex and
Co-administration of Quercetin and NLRP3 Inhibitor Attenuates Inflammation and Oxidative Stress in Cuprizone-Induced Demyelination Model
Study Overview The study investigates the effects of co-administering quercetin, a natural flavonoid known for its anti-inflammatory properties, alongside NLRP3
Simultaneous quantification of donepezil and memantine by HPLC-refractive index detection for novel drug delivery systems
Study Overview The study presents a comprehensive examination of a novel analytical approach for the simultaneous quantification of donepezil and
Fluorescent nanodiamond and gold nanoparticle hybrid-embedded contact lenses for multifunctional ocular therapy
Study Overview The research investigates the integration of fluorescent nanodiamonds and gold nanoparticles into contact lenses, aimed at advancing ocular
Systemic implications of osteoarthritis: from local degeneration to systemic metabolic Dysregulation
Systemic Effects of Osteoarthritis Osteoarthritis, traditionally perceived as a localized joint disorder, has increasingly been recognized for its broader systemic
Growth hormone deficiency following traumatic brain injury in adults: Still much of a clinical enigma
Growth Hormone Role in Brain Injury Growth hormone (GH) plays a critical role in various physiological processes, including growth, metabolism,
Signaling pathways driving multiple sclerosis: From mechanisms to natural‑product interventions
Signaling Pathways in Multiple Sclerosis Multiple sclerosis (MS) is a complex autoimmune disease characterized by the immune system’s attack on
Machine learning-based identification of concomitant stroke and prognostic analysis in patients with Guillain-Barré syndrome: a retrospective study
Background and Rationale Guillain-Barré syndrome (GBS) is a rare but serious neurological disorder characterized by rapid onset muscle weakness due
First Reported Coexistence of Plasma Cell Gingivitis and Multiple Sclerosis: A Case Report
Case Presentation A 42-year-old female presented with symptoms that included persistent oral discomfort and swelling of the gingiva. The patient