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personalized treatment

Traumatic brain injury
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Study Overview This comprehensive review focuses on the advances in the management of acute migraine …

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Traumatic brain injury
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health …

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Dementia
Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson’s disease and Lewy Body Dementia cohorts

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Study Overview This research investigates the presence and significance of expanded and interrupted repeat expansions …

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Traumatic brain injury
Acupuncture for Mild Traumatic Brain Injury: A Call for Deeper Analysis of Symptoms and Scans

by myneuronews November 25, 2025

by myneuronews November 25, 2025

Understanding Acupuncture Acupuncture is a traditional Chinese medicine practice that has gained popularity worldwide as …

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Dementia
The CSF Levels of Mitochondrial Phosphoenolpyruvate Carboxykinase 2 as a Novel Biomarker in Alzheimer’s Disease

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels …

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Dementia
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits …

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Traumatic brain injury
Physiatry Reviews for Evidence in Practice (PREP) Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: “Context of Injury and Clinical Trajectories After Mild Traumatic Brain Injury”

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview The investigation centers on the aftermath of mild traumatic brain injuries (mTBI), specifically …

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Traumatic brain injury
Comparison of Pre-injury and Clinical Characteristics Between Adolescents With Sport-Related Concussion and Non-Sport-Related Concussion Presenting to a Specialty Concussion Clinic

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview In recent years, the prevalence and recognition of concussions, particularly in adolescent populations, …

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Traumatic brain injury
Fear Avoidance after Concussion Tool (FACT): patient-reported outcome measure development and content validation

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The development of the Fear Avoidance after Concussion Tool (FACT) was initiated to …

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Traumatic brain injury
Objective Markers for Diagnosing Concussions: Beyond Blood Biomarkers and the Role of Real-Time Diagnostic Tools

by myneuronews November 13, 2025

by myneuronews November 13, 2025

Diagnostic Innovations Recent advancements in concussion diagnostics have shown promise in enhancing the speed and …

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National and subnational burden of neurological disorders in Iran, 1990 to 2021: results from the global burden of disease study 2021
Burden of Neurological Disorders in Iran The landscape of neurological disorders in Iran presents a…
Nuclear membrane disruption in neurodegenerative diseases: Emerging perspectives
Nuclear membrane function in neuronal health The nuclear membrane, or nuclear envelope, is a critical…
Cognitive impairment and altered structural connectivity after mild traumatic brain injury: A longitudinal study based on generalized q-sampling imaging
Cognitive Impairment Assessment The assessment of cognitive impairment following mild traumatic brain injury (mTBI) is…
Prevalence and Risk of Anxiety and Depression after Concussion: A TRANSCENDENT Study
Study Overview The investigation focused on the prevalence and risk factors associated with anxiety and…
Inhibition of p38 MAPK after repetitive mTBI ameliorates immune signaling and functional deficits
Study Overview This study investigates the effects of inhibiting p38 MAPK (mitogen-activated protein kinase) following…

Severity of physical, emotional, and cognitive symptoms is associated with future persistence of acute post-traumatic headache attributed to mild traumatic brain injury
AimPost-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) frequently co-occurs with other physical, cognitive, and emotional symptoms. This study assessed associations between PTH improvement and these symptoms in individuals with acute headaches (APTH) and compared symptoms between those who had recently developed persistent PTH (PPTH) to those who had long-standing PPTH.MethodsThis study included […]
NSAID Use Is Not Associated With Persisting Symptoms in Adolescent Concussion
CONCLUSIONS: In adolescents, NSAID use was associated with more severe symptoms but not PSaC. To optimize clinical guidance, future research should further evaluate the role of NSAIDs in concussion recovery.
Systemic inflammation and its associations in acute moderate-severe Traumatic Brain Injury: a cross-sectional study
Traumatic Brain Injury (TBI) triggers an acute systemic inflammatory response, which may impact outcomes. This response may interact with pre-existing factors linked to inflammation, such as age, to influence outcomes. Previous studies have typically measured few cytokines, but high-dimensional proteomic approaches can sensitively detect a broad range of inflammatory markers, to better characterise post-TBI inflammation. […]
Reduced cortical excitability is associated with head impact severity and cognitive symptoms in adolescent football players
American tackle football is associated with high rates of concussion, leading to neurophysiological disturbances and debilitating clinical symptoms, but previous investigations have largely ignored aperiodic neurophysiological activity. In this study, we use pre- and post-season resting-state magnetoencephalography (MEG) to examine whether concussion during a season of football is related to changes in neurophysiology and whether […]
Structural brain differences in professional Australian rules footballers following mild traumatic brain injury: When head size matters
INTRODUCTION: Concussion, a type of mild traumatic brain injury common in collision sports, is thought to be associated with subtle brain changes that are not visually appreciable on conventional neuroimaging. This study quantified differences in subcortical volumes from structural MRI between 31 recently concussed professional Australian rules footballers (within 3 months of injury) and 37 […]