Tag:

proteomics

Traumatic brain injury
Mechanisms of naozhenning in inhibiting neuronal ferroptosis and alleviating brain recurrent mild traumatic brain injury in a rat model

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Mechanisms of Ferroptosis Inhibition Ferroptosis is a distinct form of regulated cell death characterized by …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Non-Targeted Analysis of Extracellular Vesicle-Enriched Plasma Proteome Between Early and Late Rugby Playing Career

by myneuronews November 30, 2025

by myneuronews November 30, 2025

Study Overview This research investigates the differences in the proteomic profiles of extracellular vesicles (EVs) …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers in Epilepsy Recent research has increasingly focused on serum biomarkers as valuable tools …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers Overview Serum biomarkers have emerged as a critical aspect of understanding and diagnosing …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice

by myneuronews October 9, 2025

by myneuronews October 9, 2025

Study Overview This study investigates the effects of exercise on molecular changes following a mild …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes During Glial Scar Formation After a traumatic brain injury (TBI), the brain undergoes …

Read more

0 Facebook Twitter Pinterest Email

Current trends and projections for potential acupuncture needs globally and in China: evidence from the Global Burden of Disease Study 2021
Global Acupuncture Needs Assessment The assessment of global acupuncture needs involves a multi-faceted approach that…
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia
Study Overview The focus of this research is on exploring the potential of plasma extracellular…
Development and Evaluation of Upper Extremity Movement Quality Outcome Measures for Individuals with Functional Movement Disorder
Methodology for Movement Quality Assessment The study employed a comprehensive methodology for assessing upper extremity…
The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
Assessment Framework The evaluation of acute sport-related concussions necessitates a multidimensional approach that integrates various…
Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
Study Background The relationship between head trauma and its subsequent effects on children’s sleep patterns…

Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.
Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Appropriateness of imaging requests for pediatric traumatic brain injury in the emergency department: a retrospective cross-sectional study
CONCLUSION: A significant gap exists between clinical practice and guideline-based imaging for pediatric TBI in Chile. Reinforcing validated decision tools may help optimize imaging use and minimize unnecessary radiation exposure.
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Chronic neuroinflammation is recognized as a pivotal mechanism responsible for secondary damage following mild traumatic brain injury (mTBI), underscoring the critical need for therapeutic strategies capable of mitigating this pathological process. This study evaluated the anti-inflammatory properties of stearidonic acid ethanolamide (SDEA, C20H33NO2). The findings indicate that mTBI triggers persistent neuroinflammation, which is correlated with […]
Stability of salivary microRNA measures across an NCAA Division I football season: Implications for microRNA as a biomarker of concussion
CONCLUSIONS: Our study found no significant differences in time points for target microRNA, but ICC statistics indicated low reliability across the season. These findings suggest that microRNA expression may be variable throughout the season regardless of concussive trauma, and clinicians should be aware that changes in microRNA expression should not be directly attributed to concussive […]