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proteomics

Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomics Techniques in Glycine Receptor Analysis Understanding the complex interactions within neuronal proteins is critical …

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Medical professionals Traumatic brain injury
Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

by Ioannis Mavroudis March 22, 2024

by Ioannis Mavroudis March 22, 2024

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

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Current trends and projections for potential acupuncture needs globally and in China: evidence from the Global Burden of Disease Study 2021
Global Acupuncture Needs Assessment The assessment of global acupuncture needs involves a multi-faceted approach that…
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia
Study Overview The focus of this research is on exploring the potential of plasma extracellular…
Development and Evaluation of Upper Extremity Movement Quality Outcome Measures for Individuals with Functional Movement Disorder
Methodology for Movement Quality Assessment The study employed a comprehensive methodology for assessing upper extremity…
The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
Assessment Framework The evaluation of acute sport-related concussions necessitates a multidimensional approach that integrates various…
Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
Study Background The relationship between head trauma and its subsequent effects on children’s sleep patterns…

Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.
Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Appropriateness of imaging requests for pediatric traumatic brain injury in the emergency department: a retrospective cross-sectional study
CONCLUSION: A significant gap exists between clinical practice and guideline-based imaging for pediatric TBI in Chile. Reinforcing validated decision tools may help optimize imaging use and minimize unnecessary radiation exposure.
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Chronic neuroinflammation is recognized as a pivotal mechanism responsible for secondary damage following mild traumatic brain injury (mTBI), underscoring the critical need for therapeutic strategies capable of mitigating this pathological process. This study evaluated the anti-inflammatory properties of stearidonic acid ethanolamide (SDEA, C20H33NO2). The findings indicate that mTBI triggers persistent neuroinflammation, which is correlated with […]
Stability of salivary microRNA measures across an NCAA Division I football season: Implications for microRNA as a biomarker of concussion
CONCLUSIONS: Our study found no significant differences in time points for target microRNA, but ICC statistics indicated low reliability across the season. These findings suggest that microRNA expression may be variable throughout the season regardless of concussive trauma, and clinicians should be aware that changes in microRNA expression should not be directly attributed to concussive […]

proteomics

Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies