Biomarkers
Definition and Types Biomarkers are measurable indicators that reflect physiological, pathological processes, or responses to therapeutic interventions within the body. […]
Basic Science and Pathogenesis
Understanding Pathogenesis Pathogenesis refers to the intricate mechanisms and processes through which diseases develop and progress within an organism. It
Basic Science and Pathogenesis Read Post »
Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer’s Disease mouse model
Biological Considerations When investigating Alzheimer’s disease through animal models, particularly the 5xFAD mouse model, it is crucial to acknowledge the
Mechanisms of naozhenning in inhibiting neuronal ferroptosis and alleviating brain recurrent mild traumatic brain injury in a rat model
Mechanisms of Ferroptosis Inhibition Ferroptosis is a distinct form of regulated cell death characterized by an accumulation of lipid peroxides
Non-Targeted Analysis of Extracellular Vesicle-Enriched Plasma Proteome Between Early and Late Rugby Playing Career
Study Overview This research investigates the differences in the proteomic profiles of extracellular vesicles (EVs) derived from plasma samples of
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end products of cellular processes—in biological
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators
Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, primarily classified into three categories:
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis
Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained significant attention as researchers seek
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25
Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in diameter and are produced by
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice
Study Overview This study investigates the effects of exercise on molecular changes following a mild traumatic brain injury (mTBI) in
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice Read Post »