Study Overview This study centers on the intricate relationships between cellular profiles in the human …
transcriptomics
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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
by myneuronewsby myneuronewsMetabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …
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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders
by myneuronewsby myneuronewsRole of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …
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Functional neurological disorders
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease
by myneuronewsby myneuronewsIntegrated Transcriptomic Approaches The integration of transcriptomic approaches offers a powerful way to glean insights …
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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells
by myneuronewsby myneuronewsMetabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …
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Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection
by myneuronewsby myneuronewsMetabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …
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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice
by myneuronewsby myneuronewsStudy Overview This investigation delves into the complexities of brainstem alterations in male mice, specifically …
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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice
by myneuronewsby myneuronewsStudy Overview The research investigates the brainstem’s cellular and molecular properties in male mice, specifically …
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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2
by myneuronewsby myneuronewsBackground of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …
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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes
by myneuronewsby myneuronewsRole of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …
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