Tag:

transcriptomics

Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview This investigation delves into the complexities of brainstem alterations in male mice, specifically …

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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview The research investigates the brainstem’s cellular and molecular properties in male mice, specifically …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Functional neurological disorders
Scar-associated macrophages and biliary epithelial cells interaction exacerbates hepatic fibrosis in biliary atresia

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Mechanisms of Macrophage and Biliary Epithelial Cell Interaction The interaction between macrophages and biliary epithelial …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Headaches
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Background on Migraine and Genomics Migraine is a prevalent and often debilitating neurological condition characterized …

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Stroke
Proteome-Wide Genetic Study in East Asians and Europeans Identified Multiple Therapeutic Targets for Ischemic Stroke

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Genetic Insights into Ischemic Stroke Ischemic stroke, a condition where blood flow to the brain …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomics Techniques in Glycine Receptor Analysis Understanding the complex interactions within neuronal proteins is critical …

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Medical professionals Traumatic brain injury
Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

by Ioannis Mavroudis March 22, 2024

by Ioannis Mavroudis March 22, 2024

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

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Nerve ultrasound of multifocal motor neuropathy, motor and typical chronic inflammatory demyelinating neuropathy
Overview of Nerve Ultrasound Techniques Nerve ultrasound has emerged as a vital tool in the…
LAG3 Is Expressed on Muscle-Infiltrating Cytotoxic T Cells, but Scarce on Circulating T Cells, in Patients With Inclusion Body Myositis
Muscle-Infiltrating Cytotoxic T Cells The study of muscle-infiltrating cytotoxic T cells is essential for understanding…
A case of severe hypernatremia in a cachectic patient hospitalized for pneumococcal pneumonia
Case Presentation A 67-year-old female patient with a medical history notable for chronic obstructive pulmonary…
A neglected zoonotic helminth-Hymenolepis nana, fatal in the pediatric population-an incidental finding
Understanding Hymenolepis nana Hymenolepis nana, commonly referred to as the dwarf tapeworm, is a small…
Incidence of Opioid Use Before and After Parkinson’s Disease Diagnosis
Opioid Use Patterns The patterns of opioid use, particularly among individuals with Parkinson’s disease, reveal…

Volumetric and Diffusion Tensor Imaging Abnormalities Are Associated With Behavioral Changes Post-Concussion in a Youth Pig Model of Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) caused by sports-related incidents in children and youth often leads to prolonged cognitive impairments but remains difficult to diagnose. In order to identify clinically relevant imaging and behavioral biomarkers associated concussion, a closed-head mTBI was induced in adolescent pigs. Twelve (n = 4 male and n = 8 female), 16-week […]
Virtual reality-based eye tracking throughout typical concussion recovery
Objective: The purpose of this study was to determine the effects of concussion on visual and oculomotor function using a virtual reality-based eye tracking system throughout recovery. Design: A prospective, longitudinal cohort design assessed at the subacute, return-to-activity, and 6-month timepoints was used. Methods: Recently concussed (n = 21; age = 30 ± 14) and […]
The development and evaluation of a concussion education workshop for Gaelic games
Concussions are frequent in Gaelic games and risky behaviours following a concussion are common. With the imminent integration of the Gaelic Athletic Association, Ladies Gaelic Football Association and Camogie Association, the development of a standardised concussion education initiative for all Gaelic games members is warranted. Thus, we aimed to develop a standardised concussion education workshop […]
Atypical Symptoms Following Concussion: A Comprehensive Review of Functional Deficits
CONCLUSION: While most patients eventually improved with targeted interventions like speech therapy, psychiatric care, or physical therapy, recovery trajectories varied significantly. Larger prospective studies are needed to determine true incidence rates and establish evidence-based treatment protocols.
Transcranial Photobiomodulation Improves Cognitive Function, Post-Concussion, and PTSD Symptoms in Mild Traumatic Brain Injury
Traumatic brain injury (TBI) occurs in millions of people globally each year, with mild TBI (mTBI) representing over 90% of cases. Despite the common assumption of full recovery, significant disturbances persist in many patients with mTBI, including cognitive deficit, headache, dizziness, sleep problems, and symptoms of post-traumatic stress disorder (PTSD). Given that effective treatment is […]