Tag:

transcriptomics

Traumatic brain injury
Mechanisms of naozhenning in inhibiting neuronal ferroptosis and alleviating brain recurrent mild traumatic brain injury in a rat model

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Mechanisms of Ferroptosis Inhibition Ferroptosis is a distinct form of regulated cell death characterized by …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Integrated Transcriptomic Approaches The integration of transcriptomic approaches offers a powerful way to glean insights …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

Read more

0 Facebook Twitter Pinterest Email
Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Metabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview This investigation delves into the complexities of brainstem alterations in male mice, specifically …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview The research investigates the brainstem’s cellular and molecular properties in male mice, specifically …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

Read more

0 Facebook Twitter Pinterest Email

Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis
Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in…
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective
Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders…
DCPat-XFE: an explainable EEG model for psychogenic nonepileptic seizure detection
Study Summary The study presents the DCPat-XFE model, designed to enhance the detection of psychogenic…
Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
Study Overview The focus of this scoping review is to explore the prevalence of vestibular…
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
Study Overview The article investigates the relationship between engagement in sports and physical activities and…

Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
CONCLUSION: Vestibular dysfunction is prevalent among individuals with moderate-to-severe TBI, although the methods of assessment vary. Future studies should aim to be more consistent in documenting the severity of TBI, the evaluation of vestibular dysfunction, and determining interventions that are most beneficial for this population.
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
CONCLUSION: Participation in soccer and/or climbing showed positive associations with mTBI, while participation in yoga showed a negative association. Sports/PA participation was related to better behavioral/emotional and neurocognitive functioning, regardless of children's injury history.
Educational Perspectives on Compassionate Concussion Care: A Scoping Review
CONCLUSION: This review highlights the implicit paradigms shaping concussion-care education and their limitations for cultivating compassion. Constructivism offers the most promise for advancing compassionate practice by fostering collaboration, reflection, and learner agency. Given the interpersonal, cognitive and contextual demands of concussion care, adopting a constructivist orientation may better prepare physicians to meet patient and caregiver […]
A challenge to improve the Quality of Care.Rehabilitation outcome measures in the Emergency Department: a scoping review
CONCLUSIONS: The use of validated outcome measures by physiotherapists in EDs is feasible and clinically valuable; however, a lack of standardization and limited high-quality evidence particularly within the Italian healthcare context highlight the need for further research to establish shared outcome sets and transferable models of care.
Gaps in Access to Cognitive Rehabilitation Referrals Among Veterans with Mild Traumatic Brain Injury
CONCLUSIONS: These results suggest that while cognitive rehabilitation services tend to be allocated to those in need, significant gaps in access exist. Findings lay the foundation for developing strategies that expand access to beneficial cognitive rehabilitation among Veterans with mTBI, reducing their cognitive symptoms and enhancing their daily function.