Biomarker Definition and Types Biomarkers are biological indicators that are used to measure and evaluate …
Tag:
transcriptomics
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Dementia
Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer’s Disease mouse model
by myneuronewsby myneuronewsBiological Considerations When investigating Alzheimer’s disease through animal models, particularly the 5xFAD mouse model, it …
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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics
by myneuronewsby myneuronewsStudy Overview This research explores the phenomenon of ferroptosis, a form of regulated cell death …
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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics
by myneuronewsby myneuronewsResearch Context The brain is a complex organ with numerous cellular interactions, and understanding these …
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Traumatic brain injury
Mechanisms of naozhenning in inhibiting neuronal ferroptosis and alleviating brain recurrent mild traumatic brain injury in a rat model
by myneuronewsby myneuronewsMechanisms of Ferroptosis Inhibition Ferroptosis is a distinct form of regulated cell death characterized by …
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Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology
by myneuronewsby myneuronewsStudy Overview This study centers on the intricate relationships between cellular profiles in the human …
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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
by myneuronewsby myneuronewsMetabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …
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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders
by myneuronewsby myneuronewsRole of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …
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Functional neurological disorders
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease
by myneuronewsby myneuronewsIntegrated Transcriptomic Approaches The integration of transcriptomic approaches offers a powerful way to glean insights …
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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells
by myneuronewsby myneuronewsMetabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …
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