Tag:

transcriptomics

Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview This investigation delves into the complexities of brainstem alterations in male mice, specifically …

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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview The research investigates the brainstem’s cellular and molecular properties in male mice, specifically …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Functional neurological disorders
Scar-associated macrophages and biliary epithelial cells interaction exacerbates hepatic fibrosis in biliary atresia

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Mechanisms of Macrophage and Biliary Epithelial Cell Interaction The interaction between macrophages and biliary epithelial …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Headaches
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Background on Migraine and Genomics Migraine is a prevalent and often debilitating neurological condition characterized …

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Stroke
Proteome-Wide Genetic Study in East Asians and Europeans Identified Multiple Therapeutic Targets for Ischemic Stroke

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Genetic Insights into Ischemic Stroke Ischemic stroke, a condition where blood flow to the brain …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomics Techniques in Glycine Receptor Analysis Understanding the complex interactions within neuronal proteins is critical …

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Medical professionals Traumatic brain injury
Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

by Ioannis Mavroudis March 22, 2024

by Ioannis Mavroudis March 22, 2024

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

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Effectiveness of disease-modifying agents in ameliorating multiple sclerosis – A cross-sectional observational study
Study Overview This research was designed to assess the efficacy of disease-modifying agents (DMAs) in…
Systemic Neisseria sicca Infection Associated With Ravulizumab Therapy in Myasthenia Gravis
Study Overview The research focuses on the implications of Ravulizumab therapy in patients suffering from…
Aortic stenosis intricacies beyond the valve: A bidirectional Mendelian randomization study
Study Overview This study explores the multifaceted relationships surrounding aortic stenosis, a condition characterized by…
Effectiveness of Instrument-assisted Soft-tissue Mobilization Versus Dry Cupping on Pain and Cervical Range of Motion in Treatment of Neck Pain
Study Overview The research compares two therapeutic techniques, instrument-assisted soft tissue mobilization (IASTM) and dry…
Metabolic abnormalities of the cortico‑striato‑thalamo‑cortical circuit of rats with tic disorder
Metabolic Alterations in Tic Disorders Research into tic disorders has revealed significant metabolic changes that…

Subsequent Emergency Department Visits in Geriatric Mild Traumatic Brain Injury: Relationship with Fall, Payor, and Discharge Outcome
Background/Objectives: Older adults (ages ≥ 65) have experienced longer recovery, decreased independence in self-care, and reduced quality of life after diagnosis of mild traumatic brain injury (mTBI). Although the sequela following mTBI has also generated higher healthcare costs in older adults, the research on associations returning to the emergency department (ED) has been limited. This […]
Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) often leads to persistent cognitive and emotional symptoms, but the underlying neurobiological mechanisms remain unclear. Although previous studies have reported alterations in resting-state brain activity in mTBI patients, the findings have been inconsistent, and the genetic basis of these changes has not been fully explored. A coordinate-based voxel-wise meta-analysis was […]
Depression Symptoms Associated With Clinical Symptoms, Disability, and Functional Connectivity After Traumatic Brain Injury
CONCLUSIONS: The findings suggest that depression after TBI may not be a unitary syndrome but rather may be composed of clusters of symptoms that have different associations with TBI symptom burden, disability, and brain connectivity.
The Polytrauma Clinical Triad Among Women with a History of Intimate Partner Violence
Women with a history of intimate partner violence (IPV) are at risk for traumatic brain injury (TBI) with persistent neurobehavioral symptoms, post-traumatic stress disorder (PTSD), and chronic pain, which, together, characterize the polytrauma clinical triad. Among predominantly male Veteran samples, research has suggested that the triad may exacerbate health problems, compared with the presence of […]
Understanding Beliefs and Perceptions of Parents, Coaches, and Organizational Leaders toward Non-concussive Head Impact Exposure in Youth American Football
Concussions are a prevalent public health concern; however, non-concussive head impacts without signs and symptoms of concussion may have a greater influence on brain health. The objective of this study was to apply components of the health belief model to perceptions of non-concussive head impacts and preventative efforts to reduce head impacts in youth American […]