Altered microstate dynamics in Functional Neurological Disorder

February 26, 2026

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Functional Neurological Disorder Management in a Pediatric Hospital: A Retrospective Chart Review
Background Information Functional Neurological Disorder (FND) is characterized by a range of neurological symptoms that cannot be explained by a defined neurological or medical condition. These symptoms may include movement disorders, seizures, and sensory disturbances, which can significantly impair a patient’s daily functioning. In children and adolescents, FND is particularly challenging as its clinical presentation… Read more: Functional Neurological Disorder Management in a Pediatric Hospital: A Retrospective Chart Review
Functional Neurological Disorder Management in a Pediatric Hospital: A Retrospective Chart Review
Study Overview The research explored the management of Functional Neurological Disorder (FND) within a pediatric hospital context, utilizing a retrospective chart review method. FND, characterized by neurological symptoms that cannot be attributed to an identifiable medical condition, poses unique challenges in diagnosis and treatment, particularly among children. The study aimed to analyze clinical practices, treatment… Read more: Functional Neurological Disorder Management in a Pediatric Hospital: A Retrospective Chart Review
Guillain-Barré Syndrome As the Initial Manifestation of Human Immunodeficiency Virus Infection: A Case Report
Clinical Presentation Guillain-Barré Syndrome (GBS) is an acute neurological disorder characterized by the rapid onset of muscle weakness and paralysis. In the context of an initial manifestation of Human Immunodeficiency Virus (HIV) infection, the clinical presentation can be particularly varied and may pose challenges for early diagnosis. Patients typically present with progressive limb weakness, often… Read more: Guillain-Barré Syndrome As the Initial Manifestation of Human Immunodeficiency Virus Infection: A Case Report
Perfusion imaging predicts therapeutic cooling response and tracks cis-p-tau pathology in porcine brain injuries
Study Overview The research investigates the relationship between perfusion imaging and the effectiveness of therapeutic cooling in managing brain injuries in porcine models. The focus is on understanding how changes in blood flow can predict the response to cooling therapy and provide insights into the pathology associated with cis-p-tau proteins, which are implicated in neurodegenerative… Read more: Perfusion imaging predicts therapeutic cooling response and tracks cis-p-tau pathology in porcine brain injuries
The Pharmacist’s Paradox: Burnout, Financial Optionality and Career Sustainability
Pharmacy Profession Landscape The pharmacy profession is undergoing significant transformations driven by multiple factors, including technological advancements, shifts in healthcare delivery models, and evolving patient care expectations. Traditionally viewed as dispensers of medication, pharmacists are increasingly embracing roles that emphasize clinical care, patient education, and interdisciplinary collaboration. This evolution reflects a broader focus within healthcare… Read more: The Pharmacist’s Paradox: Burnout, Financial Optionality and Career Sustainability

Circulating oligodendrocyte-derived extracellular vesicle surface markers in athletes exposed to repetitive head impacts: an exploratory study
CONCLUSION: Surface-associated biomarkers on circulating ODEs demonstrated measurable longitudinal changes in subsets of athletes with expected exposure to RHI. These exploratory findings support prospective studies combining ODE-associated biomarker measurements with quantitative head-impact monitoring, clinical characterization, neuroimaging, and neurological outcomes to determine their biological and clinical significance.
Functional recovery of patients with moderate and severe traumatic brain injury after extended and standard early rehabilitation
CONCLUSION: Although no statistically significant difference on functional recovery between the groups was found, however, a difference in percentage progress was found in favor of extended early rehabilitation, but for a final conclusion it is necessary to make a follow-up after inpatient rehabilitation.
Integration of S100B and GFAP with the PECARN Rule for CT Decision-Making in Pediatric Mild Traumatic Brain Injury: A Preliminary Study
CONCLUSIONS: Our preliminary findings suggest that the addition of S100B and GFAP to the PECARN algorithm could refine CT decision-making in pediatric mild TBI. Within the PECARN intermediate-to-high risk subgroup, serum S100B levels below 2667.14 ng/L and GFAP levels below 61.1 pg/mL may identify patients in whom CT could potentially be deferred. However, larger cohort […]
Impact of on-site mobile CT imaging on prehospital patient management during the Munich Oktoberfest: a retrospective observational before-after study at a mass gathering
CONCLUSION: This retrospective analysis of the use of a mobile CT scanner in a prehospital setting during a mass gathering found that its implementation was associated with improved patient triage, fewer hospital transports, and more efficient EMS resource utilization. While the retrospective before-after study design does not permit direct causal inference, on-site imaging may have […]
Impact of non-credible cognitive performance on multidisciplinary treatment outcomes in youth with persisting symptoms after concussion
This study characterizes patterns of non-credible cognitive performance, clinical presentations and functional outcomes, and multidisciplinary treatment response in youth with persisting symptoms after concussion. A retrospective analysis of demographic data, injury factors, symptom ratings, and functional outcomes was conducted in 136 patients (8-20 years-old; 64% female) presenting for multidisciplinary concussion care. Concussion mechanisms included sports, […]

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