Astasia-Abasia Syndrome

April 24, 2025

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Clinical Presentations and Treatment Experiences of Functional Neurological Disorder in the Perinatal Period
Clinical Presentations Functional Neurological Disorder (FND) during the perinatal period manifests in various clinical presentations that can significantly affect the physical and psychological well-being of affected individuals. Recognizing these presentations is crucial for timely diagnosis and appropriate management. The symptoms of FND in the perinatal population may resemble those of neurological disorders such as seizures… Read more: Clinical Presentations and Treatment Experiences of Functional Neurological Disorder in the Perinatal Period
Temporal astrocytic metabolic reprogramming gates pain chronification
Astrocytic Metabolism and Pain Astrocytes, a type of glial cell in the brain and spinal cord, play a crucial role in maintaining homeostasis and supporting neuronal function. Recent studies have revealed that these cells are not merely supportive entities; they are actively involved in the metabolic processes that contribute to pain regulation. The metabolism of… Read more: Temporal astrocytic metabolic reprogramming gates pain chronification
Clinical Presentations and Treatment Experiences of Functional Neurological Disorder in the Perinatal Period
Clinical Presentations Functional Neurological Disorder (FND) presents with a variety of clinical symptoms that can significantly impact individuals during the perinatal period. These symptoms may manifest interchangeably, often challenging both patients and healthcare providers. Common clinical manifestations include motor dysfunctions, sensory disturbances, and episodes of seizures that do not have a neurological basis. Women may… Read more: Clinical Presentations and Treatment Experiences of Functional Neurological Disorder in the Perinatal Period
Case Report: Diffuse large B-cell lymphoma presenting predominantly with spinal cord involvement: a series of three cases confirmed by abdominopelvic lymph node biopsy
Clinical Presentation Diffuse large B-cell lymphoma (DLBCL) is a prevalent form of non-Hodgkin lymphoma characterized by the rapid proliferation of malignant B-cells. In the three cases discussed, the initial clinical presentations were atypical, predominantly manifesting as neurological symptoms due to spinal cord involvement. Patients presented with localized back pain, often severe and worsening over time,… Read more: Case Report: Diffuse large B-cell lymphoma presenting predominantly with spinal cord involvement: a series of three cases confirmed by abdominopelvic lymph node biopsy
Anti-TNF-Alpha Associated Central Nervous System Demyelination. Drug-Induced Demyelination or Multiple Sclerosis Trigger? A Case Series
Study Overview This study investigates the potential correlation between the use of anti-TNF-alpha therapies and the development of central nervous system (CNS) demyelination. While anti-TNF-alpha agents are primarily utilized in the treatment of inflammatory conditions such as rheumatoid arthritis and Crohn’s disease, emerging reports have suggested an unexpected risk regarding neurological complications associated with their… Read more: Anti-TNF-Alpha Associated Central Nervous System Demyelination. Drug-Induced Demyelination or Multiple Sclerosis Trigger? A Case Series

Comment on: "Examining the Recovery Course of Adolescent Concussion Patients With Protracted Recovery Referred to a Specialty Concussion Clinic"
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Alcohol use, vision therapy, children, mood what predicts post-traumatic growth after concussion in women?
CONCLUSION: This exploratory study highlights key demographic and psychosocial factors linked to PTG in women recovering from concussion. Modifiable characteristics such as resilience, flourishing, and lifestyle stability, particularly return to work and absence of alcohol use-were associated with higher PTG, offering potential intervention targets and helping to identify individuals who may require more intensive post-concussion […]
Near and distance vergence facility provides complementary clinical information in concussion-related convergence insufficiency
CONCLUSIONS: Near and distance vergence facility testing provided complementary rather than interchangeable clinical information in adolescents and young adults with concussion-related convergence insufficiency. Both measures improved following vergence/accommodative therapy, supporting consideration of both testing distances in clinical assessment.
Diagnostic challenge of GAD65-associated autoimmune encephalitis mimicking post-traumatic complications in an older adult: a case report
CONCLUSION: Traumatic brain injury may obscure the onset of GAD65-associated autoimmune encephalitis. Early recognition and a corticosteroid-sparing immunotherapy strategy (IVIG and azathioprine) can yield favorable outcomes in elderly patients with medical comorbidities.
Concurrent chronic methamphetamine exposure may influence behavioral outcomes following repetitive mild traumatic brain injury
CONCLUSIONS: Together, these findings suggest that chronic methamphetamine exposure could potentially increase long-term, but not acute, TBI-induced deficits.

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