Astasia-Abasia Syndrome

April 24, 2025

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Clinical Intelligence Report — 2026-05-31
Clinical Intelligence Report Window: Last 30 daysStudy posts included: 387 Top Conditions Unknown — 387 Study Types Unknown — 387 Modalities Unknown — 387 Biomarkers (Top 20) Outcomes (Top 20) Effect Direction Unknown — 387 Add an API key in Settings → MyNeuroNews Insights to enable the narrative brief.
The clinical role of lncRNA PRKG1-AS1 in lumbar disc degeneration and its mechanism in regulating inflammation and ferroptosis via miR-218-5p
Study Overview The investigation focuses on the role of long non-coding RNA (lncRNA) PRKG1-AS1 within the context of lumbar disc degeneration (LDD), a prevalent condition often associated with chronic back pain and disability. Recent studies have suggested that lncRNAs are crucial in various biological processes, including inflammation and cellular death pathways, both of which are… Read more: The clinical role of lncRNA PRKG1-AS1 in lumbar disc degeneration and its mechanism in regulating inflammation and ferroptosis via miR-218-5p
Idiopathic Multicentric Castleman Disease Presenting as Recurrent Acute-Onset Demyelinating Neuropathy
Study Overview The present research investigates idiopathic multicentric Castleman disease (iMCD), a rare lymphoproliferative disorder characterized by an abnormal immune response and systemic inflammation. This condition often remains underdiagnosed or misdiagnosed due to its complex and varied clinical presentations, one of which includes recurrent acute-onset demyelinating neuropathy. The objective of this study was to elucidate… Read more: Idiopathic Multicentric Castleman Disease Presenting as Recurrent Acute-Onset Demyelinating Neuropathy
Comparative effectiveness of exercise interventions on postural balance and activity ability in stroke patients: a systematic review and network meta-analysis
Study Overview This systematic review and network meta-analysis focused on evaluating the effectiveness of various exercise interventions in enhancing postural balance and activity ability among stroke patients. Stroke, a significant contributor to long-term disability, often affects motor functions and balance, leading to challenges in daily activities and increasing the risk of falls. The variability in… Read more: Comparative effectiveness of exercise interventions on postural balance and activity ability in stroke patients: a systematic review and network meta-analysis
Associations between oral migraine preventive regimens and CGRP monoclonal antibody initiation: real-world evidence from a resource-limited setting
Study Overview The increasing utilization of monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway marks a new frontier in the management of migraines, especially given the limitations often experienced with traditional oral preventive regimens. This study aims to evaluate the real-world implications of initiating CGRP monoclonal antibodies among patients who have been prescribed oral… Read more: Associations between oral migraine preventive regimens and CGRP monoclonal antibody initiation: real-world evidence from a resource-limited setting

Interdisciplinary Management of Concussion in an Adolescent With Type 1 Diabetes Mellitus: Diagnostic Challenges Related to Hypoglycemia and Cognitive Impairment
Type 1 diabetes mellitus (T1DM) can complicate recovery after mild traumatic brain injury (mTBI) by mimicking post-concussive symptoms. This case details the recovery of a 17-year-old female with T1DM who sustained an mTBI and lumbar spine fractures following a motor vehicle collision. Post-traumatic amnesia, short-term memory deficits, and impaired glucose regulation complicated her recovery. Cognitive […]
Evidence-Based Interventions for Functional Restoration and Pain Management following Traumatic Brain Injury
Traumatic brain injury is a major cause of death and long-term disability worldwide and can lead to persistent functional impairment and chronic pain that significantly impact quality of life. Patients with traumatic brain injury commonly experience motor deficits, impaired balance and coordination, cognitive dysfunction, and behavioral changes. Chronic pain, particularly post-traumatic headaches and musculoskeletal pain, […]
Setbacks to strengths: A scoping review of positive psychology constructs among veterans and service members with traumatic brain injury
CONCLUSIONS/IMPLICATIONS: An ecological framework situates PPCs across individual, social, and environmental domains, contextualizing multiple spheres of influence on recovery from TBI. Future rehabilitation research would benefit from intentional study design planning with coherent theoretical frameworks that clarify the relationships between PPCs, outcomes, and contextual factors. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
The physiological effects of APOE genotype in healthy young/middle-aged individuals
The apolipoprotein E ε4 (APOE4) allele is a risk factor for cardiovascular disease and for multiple neurodegenerative diseases, most notably Alzheimer's disease (AD). However, in healthy infants to adults, the encoded apolipoprotein E protein plays a role in many physiological functions, in both the periphery and in the brain, which can help us understand the […]
The positive predictive value of ICD-10-AM S06.0~ concussion codes for mild traumatic brain injury
CONCLUSION: There are limitations to using ICD-10-AM concussive injury codes to identify mTBI in ED settings, and patient characteristics influence coding accuracy. Reconsideration of current ED coding practices, including exploration of alternative models that reduce clinician burden and improve coding accuracy, is recommended.Implications for health information management practice:The introduction of electronic medical records provides an […]

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