Astasia-Abasia Syndrome

April 24, 2025

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The prevalence of post-traumatic stress disorder in functional / dissociative seizures: A systematic review and meta-analysis
Prevalence of PTSD in Seizure Disorders Post-traumatic stress disorder (PTSD) is a condition that can arise after exposure to traumatic events, leading to various psychological symptoms such as intrusive memories, avoidance behaviors, and heightened arousal. Research indicates a significant association between PTSD and seizure disorders, particularly functional seizure disorders. Understanding the prevalence of PTSD within… Read more: The prevalence of post-traumatic stress disorder in functional / dissociative seizures: A systematic review and meta-analysis
Real-world data on patient-reported outcomes and potential factors associated with pain after thyroid/parathyroid surgery: a prospective QUIPS registry analysis of a large cohort – sparking new pain management concepts
Study Overview The research focused on gathering real-world data regarding patient-reported outcomes, specifically centering on pain experiences following thyroid and parathyroid surgeries. This investigation utilized the framework of a prospective Quality Improvement in Pain Surgery (QUIPS) registry, designed to monitor and analyze a sizable cohort of individuals who underwent these procedures. Thyroid and parathyroid surgeries,… Read more: Real-world data on patient-reported outcomes and potential factors associated with pain after thyroid/parathyroid surgery: a prospective QUIPS registry analysis of a large cohort – sparking new pain management concepts
The prevalence of post-traumatic stress disorder in functional / dissociative seizures: A systematic review and meta-analysis
Study Overview This systematic review and meta-analysis aimed to explore the prevalence of post-traumatic stress disorder (PTSD) among individuals experiencing functional or dissociative seizures. Functional seizures, which are often characterized by abnormal movements or behaviors that resemble epileptic seizures, occur in the absence of a neurological basis. Dissociative seizures, a subtype of functional seizures, may… Read more: The prevalence of post-traumatic stress disorder in functional / dissociative seizures: A systematic review and meta-analysis
Predictors of Multiple Sclerosis After Clinically Isolated Syndrome: A Systematic Review and Meta-Analysis
Research Context Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, characterized by demyelination and neurodegeneration. Clinically Isolated Syndrome (CIS) refers to the first episode of neurological symptoms caused by inflammation and demyelination, which may indicate the potential onset of MS. Understanding which factors may predict the progression from CIS to… Read more: Predictors of Multiple Sclerosis After Clinically Isolated Syndrome: A Systematic Review and Meta-Analysis
Case Report: Schwann cell reprogramming and PDGF-driven nerve hypertrophy in an NF1 patient with CIDP-like autoimmunity
Study Overview The investigation presented in this case report revolves around the intricate relationship between Schwann cell behavior and the pathogenic mechanisms underlying a patient’s unique clinical situation involving neurofibromatosis type 1 (NF1) and a phenotype resembling Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). The cohesive narrative focuses on how alterations in Schwann cell functionalities contribute to… Read more: Case Report: Schwann cell reprogramming and PDGF-driven nerve hypertrophy in an NF1 patient with CIDP-like autoimmunity

Diffusion MRI Profiles Map onto Distinct Inflammatory States After Adolescent Concussion: A CARE4Kids Study
CONCLUSIONS AND RELEVANCE: Multiple diffusion MRI metrics are differentially sensitive to distinct neuroinflammatory states in the subacute period after adolescent concussion. These findings suggest that diffusion imaging could serve as a non-invasive tool for inflammatory phenotyping, with potential implications for identifying patients who may benefit from targeted immunomodulatory intervention.
Transglutaminase 2 Deletion Enhances Astrocyte-to-Neuron Metabolic Support and Attenuates Subacute Pathology Following Repetitive Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) is the most common form of central nervous system (CNS) injury and is often characterized by persistent neuroinflammation, metabolic dysregulation, and oxidative stress. Repetitive injuries compound these pathologies and lead to multifocal axonal injuries and long-term functional deficits. Despite the prevalence of mTBIs, the cellular mechanisms that facilitate or prevent […]
Longitudinal White Matter Changes in Concussed Adolescents with Adverse Childhood Experiences
Traumatic brain injury (TBI) is a leading cause of death and long-term disability in children, with many experiencing persistent symptoms even after mild TBIs. Exposure to adverse childhood experiences (ACEs) can have physiological effects that may alter how the brain responds to injury, yet the effects of ACEs on white matter injury and recovery processes […]
Persistent Symptom Burden Following Mild Traumatic Brain Injury Is Associated With Lower Quality of Life in Middle-Aged and Older Adults
Nearly one-third of individuals who sustain a mild traumatic brain injury (mTBI) experience persistent symptoms 3 months or longer, which can significantly impact their quality of life (QoL). These symptoms often span physical, cognitive, emotional, and sleep-related domains. To examine the relationship between symptom severity, QoL, and time since injury in individuals with persistent symptoms […]
Predicting Social Participation and Quality of Life in Individuals with TBI at Least One Year after Discharge from Rehabilitation
This is an original follow-up study on predictors of social participation outcomes after traumatic brain injury (TBI) in a prospective longitudinal cohort followed within a universally accessible specialized rehabilitation pathway. The analytic sample comprised 98 individuals with complete clinical data that participated in inpatient and/or outpatient rehabilitation programs at three health centers and completed the […]

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