Astasia-Abasia Syndrome

April 24, 2025

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Multibacillary Leprosy Presenting as Chronic Progressive Polyneuropathy Initially Diagnosed as Probable Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Diagnostic Pitfall
Study Overview The focus of this investigation is a case of multibacillary leprosy that presented as chronic progressive polyneuropathy, which was initially misdiagnosed as probable chronic inflammatory demyelinating polyneuropathy (CIDP). This misdiagnosis highlights a significant challenge within clinical settings, as it underscores the need for heightened awareness regarding rare but important differential diagnoses in patients… Read more: Multibacillary Leprosy Presenting as Chronic Progressive Polyneuropathy Initially Diagnosed as Probable Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Diagnostic Pitfall
Monoclonal Gammopathy of Neurologic Significance: A Practical Framework for Diagnosis and Management
Understanding Monoclonal Gammopathy Monoclonal gammopathy refers to the presence of an abnormal protein produced by cloned cells, typically a type of plasma cell. This condition often surfaces during diagnostic evaluations for various systemic symptoms or complications. The identified monoclonal protein, designated as M-protein, is a hallmark of an underlying disorder. While some individuals may experience… Read more: Monoclonal Gammopathy of Neurologic Significance: A Practical Framework for Diagnosis and Management
Bow hunter’s syndrome presenting with embolism in an older patient treated with C1-2 posterior fixation using intraoperative digital subtraction angiography: illustrative case
Study Overview This study focuses on a rare clinical case known as Bow hunter’s syndrome, which occurs when there is an obstruction of blood flow to the brain due to neck movement, primarily affecting older individuals. The specific situation examined involves a patient who experienced embolism, a blockage of blood vessels resulting from an obstruction… Read more: Bow hunter’s syndrome presenting with embolism in an older patient treated with C1-2 posterior fixation using intraoperative digital subtraction angiography: illustrative case
Ruptured giant vertebrobasilar aneurysms: illustrative cases
Study Overview The examination of ruptured giant vertebrobasilar aneurysms is critical due to their complexity and the potential for severe neurological outcomes. This study employs a thorough analysis of illustrative cases to highlight the clinical presentations, treatment strategies, and outcomes for patients suffering from these catastrophic events. By focusing on patient data from multiple clinical… Read more: Ruptured giant vertebrobasilar aneurysms: illustrative cases
Effects of Supplementation With Genistein on the Progression of Cognitive Decline in Patients With Mild Cognitive Impairment Due to Alzheimer Disease: Protocol for a Randomized Controlled Trial
Study Overview The investigation delves into the implications of genistein supplementation on the decline of cognitive abilities in individuals diagnosed with mild cognitive impairment (MCI) stemming from Alzheimer’s disease. Genistein, a natural isoflavone primarily found in soy products, has garnered attention for its potential neuroprotective properties. This study aims to elucidate whether genistein can effectively… Read more: Effects of Supplementation With Genistein on the Progression of Cognitive Decline in Patients With Mild Cognitive Impairment Due to Alzheimer Disease: Protocol for a Randomized Controlled Trial

The Validity and Reliability of a Novel Testing Device and Six-Way Neck-Strength Testing Protocol for Peak Force and Rate of Force Development
Neck strength is hypothesised to mitigate head/neck injury and head acceleration events. Studies often only assess maximal isometric neck strength in flexion, extension, and lateral flexion and few consider the criterion and ecological validity of the devices and protocols used. This study aimed to (1): evaluate the validity and reliability of a novel strength-testing device […]
Repetitive Transcranial Magnetic Stimulation in Pain Management: A Narrative Review of Randomized Controlled Trials
Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation technique widely applied in clinical practice for various conditions, including pain management. Because a proportion of patients with pain remain refractory to conventional treatments and given the promising therapeutic potential and favorable safety profile of rTMS, its application in pain management warrants comprehensive evaluation. This narrative […]
Brain Structural Changes in Blast-Exposed Special Operations Forces Soldiers
Special Operations Forces (SOF) soldiers experience frequent low-level occupational blast exposure and mild traumatic brain injury (mTBI), but the cumulative effects of these exposures on long-term neurological health remain poorly understood. The purpose of this longitudinal cohort study was to investigate associations between occupational blast exposure and brain structural change in SOF soldiers and to […]
Persistent post-concussion symptoms are associated with more cranial and upper cervical mobility restrictions as measured by manual clinical evaluation
CONCLUSION: Number of restrictions was significantly higher in the PCS group compared to the Ctl group. Additional investigation is warranted to refine the location and magnitude of restrictions with the type and severity of symptoms.
Concussion Management Practices Among Primary Care Professionals Who Care for Children and Adults With Concussions-2023 DocStyles Survey
CONCLUSION: This study found that many participants' self-reported concussion management practices do not align with clinical recommendations from the Centers for Disease Control and Prevention and others. Use of clinical care pathways, and other promising strategies to improve adherence to guideline recommendations, may be beneficial.

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