Category:

Biomarkers

Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Biomarkers Traumatic brain injury
Blood biomarkers in mTBI

by Ioannis Mavroudis June 22, 2024

by Ioannis Mavroudis June 22, 2024

Several studies have demonstrated that elevated levels of S100B, GFAP, UCH-L1, and NFL correlate with …

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Biomarkers Medical professionals Traumatic brain injury
Salivary biomarkers in Post-concussion syndrome

by Ioannis Mavroudis February 12, 2024

by Ioannis Mavroudis February 12, 2024

Traumatic brain injuries (TBIs), particularly mild TBIs, present a complex diagnostic challenge due to their …

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Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report
Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of…
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia
Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers…
Using Genetics to Shed Light on the Scientific Gray Zone of Functional Seizures
Genetic Factors in Functional Seizures Recent studies have begun to uncover the genetic underpinnings that…
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies
Study Overview This comprehensive review focuses on the advances in the management of acute migraine…
Knee Biomechanics in Individuals With a Recent Concussion During Jump-Landing Tasks
Background and Rationale The relationship between concussions and subsequent physical performance, particularly in biomechanical tasks,…

Riding at Risk: The Lifesaving Role of Helmets for Motorcycle Pillion Riders
CONCLUSION: Pillion riders sustain serious TBIs comparable to or more severe than riders. The mortality rate is substantial, particularly among those not wearing helmets. Mandatory helmet use for pillion riders could significantly reduce mortality and injury severity. Further comparative studies between riders and pillion riders are warranted to better understand injury patterns and develop targeted […]
Ryanodex Reduces Persistent Hippocampal Effects of Single Mild Traumatic Brain Injury in Rats
Traumatic brain injury (TBI) affects millions of individuals annually, with a 53% increase in emergency visits since 2006. Despite its prevalence, no FDA-approved treatments exist to mitigate brain damage or promote recovery. While repeated TBI is widely studied, even a single impact can cause persistent neurological changes, likely mediated by Ca^(2+) dysregulation via effects on […]
Letter to the Editor in Response to: Eagle SR, Henry RJ. Applying Dynamical Systems Theory to Improve Personalized Medicine Following Mild Traumatic Brain Injury. Neurotrauma Rep 2024 Jul 16;5(1):671-679; Doi: 10.1089/Neur.2024.0040
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Exploring Speech Biosignatures for Traumatic Brain Injury and Neurodegeneration: Pilot Machine Learning Study
CONCLUSIONS: This study highlights the potential of speech features as biomarkers for neurodegenerative conditions. The PaTaKa test exhibited strong discriminative ability, especially for concussed versus neurodegenerative and concussed versus healthy tasks, whereas challenges remain for neurodegenerative versus healthy classification. These findings emphasize the need for further exploration of speech-based tools for differential diagnosis and early […]
Transcranial Direct Current Stimulation in Older Adolescent with Chronic Mild Traumatic Brain Injury: A Case Study of Clinical and Functional Connectivity
This is the first case study, to our knowledge, to document pre- and post-tDCS resting-state functional MRI changes between the dorsolateral prefrontal cortex (DLPFC) and brainstem in an adolescent with chronic post-concussive symptoms following multiple mild traumatic brain injuries (mTBIs). By demonstrating that cortico-brainstem connectivity can be modulated through noninvasive neuromodulation, the novel findings of […]

Biomarkers

Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

Blood biomarkers in mTBI

Salivary biomarkers in Post-concussion syndrome