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Biomarkers

  • BiomarkersTraumatic brain injury

    Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

    by Ioannis Mavroudis November 16, 2024
    by Ioannis Mavroudis November 16, 2024

    Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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  • BiomarkersTraumatic brain injury

    Blood biomarkers in mTBI

    by Ioannis Mavroudis June 22, 2024
    by Ioannis Mavroudis June 22, 2024

    Several studies have demonstrated that elevated levels of S100B, GFAP, UCH-L1, and NFL correlate with …

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  • BiomarkersMedical professionalsTraumatic brain injury

    Salivary biomarkers in Post-concussion syndrome

    by Ioannis Mavroudis February 12, 2024
    by Ioannis Mavroudis February 12, 2024

    Traumatic brain injuries (TBIs), particularly mild TBIs, present a complex diagnostic challenge due to their …

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  • Dorsal root ganglion neuromodulation restores accumbal gate to inhibit mechanical allodynia
    Study Overview The investigation focused on the role of dorsal root ganglion (DRG) neuromodulation in…
  • Animal-assisted support programs for residents in Canadian long-term care homes: a feasibility and acceptability study
    Study Overview In recent years, there has been a growing interest in the potential benefits…
  • Sex Differences in Severity and Recovery Following Mild Traumatic Brain Injury: A Systematic Review
    Gender Differences in Brain Injury Response Research indicates that there are notable variances in how…
  • A Prefrontal Neuromodulation Route for Post-Traumatic Olfactory Dysfunction: A Perspective Supported by Recovery During Left-DLPFC rTMS
    Neuromodulation Mechanisms Neuromodulation refers to the process by which certain substances or stimuli influence the…
  • Non-Pharmacological Approaches to Addressing Overweight and Obesity in Children and Adolescents with Mental Illness: A Scoping Review of Quantitative and Qualitative Evidence
    Study Overview The research meticulously investigates the intersection of overweight and obesity in children and…

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Research

  • Beyond the Concussion: Cerebral Venous Thrombosis Following Mild-to-Moderate Traumatic Brain Injury
    Cerebral venous sinus thrombosis (CVST) accounts for a small proportion of strokes. Still, it carries meaningful clinical impact, classically linked to systemic prothrombotic conditions, hormonal influences, and severe traumatic brain injury (TBI). However, with advances in neuroimaging, it's now evident that trauma-related CVST (tCVST) can also complicate mild to moderate head injuries even in the […]
  • Network co-activation relates to executive function following pediatric traumatic brain injury
    CONCLUSIONS: Findings illustrate the implications of disrupted downregulation of the default mode network by the SN following pediatric brain injury. They also demonstrate how disruption in functional connectivity may underlie poor executive function after childhood traumatic brain injury.
  • Monitoring the lateral ventricles in the presence of intracranial hemorrhage using automated dual segmentation
    CONCLUSIONS: Automated dual segmentation of lateral ventricles and ICH using deep learning provides a reliable method to monitor TBI severity over time. The approach yielded clinically relevant information, including ICH and lateral ventricle volume changes across sessions. This approach offers an efficient analysis of CT images in ICH and particularly patients that develop IVH.
  • Quality of Life, Self-Reported Cognitive Difficulties, and Performance-Based Cognitive Problems in Multiple Sclerosis: What's Sleep Got to Do With It?
    CONCLUSIONS: Poor sleep quality was not associated with performance-based cognitive functioning but was associated with greater self-reported cognitive difficulties. After accounting for disease progression, depression, and fatigue, poor sleep quality was significantly predictive of both Symptoms and Fatigue QoL.
  • Parent and Child Agreement of Brain Injury Perceptions Following Pediatric Concussion
    CONCLUSIONS: Parent-child agreement regarding brain injury perceptions following a pediatric concussion was low (13%), reflecting the importance of assessing and then addressing parent and child perceptions individually in pediatric concussion management.

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