Category:

Biomarkers

Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Biomarkers Traumatic brain injury
Blood biomarkers in mTBI

by Ioannis Mavroudis June 22, 2024

by Ioannis Mavroudis June 22, 2024

Several studies have demonstrated that elevated levels of S100B, GFAP, UCH-L1, and NFL correlate with …

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Biomarkers Medical professionals Traumatic brain injury
Salivary biomarkers in Post-concussion syndrome

by Ioannis Mavroudis February 12, 2024

by Ioannis Mavroudis February 12, 2024

Traumatic brain injuries (TBIs), particularly mild TBIs, present a complex diagnostic challenge due to their …

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Spontaneous Regression of Cranial Vault Lymphoma: A Case Report
Case Presentation A 54-year-old male patient, previously healthy with no notable medical history, presented with…
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis
Study Overview The research aimed to investigate the role of TDP-43 accumulation in the progression…
Reframing Functional Neurological Disorders in Modern Medicine
Reframing the Understanding of FND Functional Neurological Disorder (FND) represents a complex interplay of neurological…
Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design
Study Summary This study focused on evaluating the effectiveness of inpatient cognitive analytic therapy (CAT)…
Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT
Study Summary The Physio4FMD randomized controlled trial aimed to evaluate the effectiveness of specialist physiotherapy…

Youth Ages 4 to 13 Trends of Sports Concussions With Loss of Consciousness From 2014-2023 National Electronic Injury Surveillance System
CONCLUSION: The results of this study show a decrease in the overall level of LOC incidence in US youth athletes ages 4 to 13 years from 2014 to 2023 across 8 sports. The data delineate from previous studies that show an exponential increase in LOC incidence; however, the underlying reasons are still unclear and warrant […]
Development of the Common Cognitive Complaints after Concussion (C4) questionnaire: a treatment-planning tool for military service members and veterans with mild traumatic brain injury
CONCLUSION: The C4 adequately captured activity-level functional impairments common to mTBI, and clinicians endorsed its utility as a useful tool to personalize treatment targets.
Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]
Tackle characteristics associated with concussion in elite men's rugby union: unpicking the differences between tacklers and ball-carriers
CONCLUSIONS: Lower tackles reduce the chances of concussion to ball-carriers. The influence of tackle height on concussion to tacklers is more nuanced, but the chances are relatively low when contact is made with the ball-carrier's torso. These findings support ongoing implementation of strategies to reduce concussion risk by lowering tackle height to target the torso.

Biomarkers

Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

Blood biomarkers in mTBI

Salivary biomarkers in Post-concussion syndrome