Characterisation of Chronic Pain Syndrome in Patients With Functional Neurological Disorder

February 24, 2026

Leave a Comment Cancel Reply

Pneumosinus dilatans frontalis: a cause of headaches mimicking chronic sinusitis-a case report and review of the literature
Background on Pneumosinus Dilatans Pneumosinus dilatans is a rare condition characterized by the abnormal enlargement of the paranasal sinuses, specifically the frontal sinus, due to excessive accumulation of air. This phenomenon can manifest in various ways, leading to symptoms that may closely resemble those of chronic sinusitis, including pressure and pain in the forehead region… Read more: Pneumosinus dilatans frontalis: a cause of headaches mimicking chronic sinusitis-a case report and review of the literature
Immunoregulatory Effect of Curcumin on Experimental Autoimmune Encephalomyelitis (EAE), an Animal Model of Multiple Sclerosis (MS)
Overview of Curcumin’s Effects Curcumin, the active compound derived from the turmeric plant, has garnered significant attention in the scientific community for its potential therapeutic effects, particularly in the realm of autoimmune disorders. Research has demonstrated curcumin’s ability to modulate various biochemical pathways that are pivotal in inflammatory responses, making it a noteworthy candidate for… Read more: Immunoregulatory Effect of Curcumin on Experimental Autoimmune Encephalomyelitis (EAE), an Animal Model of Multiple Sclerosis (MS)
Mechanistic insights from experimental autoimmune encephalomyelitis into immune regulation, autophagy, gut microbiota, blood-brain barrier integrity, and NLRP3 inflammasome-mediated pyroptosis in multiple sclerosis: potential clinical implications
Mechanistic Insights into Multiple Sclerosis Multiple sclerosis (MS) is characterized by an autoimmune response that targets the central nervous system, resulting in inflammation, demyelination, and neurodegeneration. The mechanisms underlying this complex disease involve a variety of interconnected factors, including the immune system’s dysregulation, the role of neuroinflammation, and various cellular pathways that contribute to neuronal… Read more: Mechanistic insights from experimental autoimmune encephalomyelitis into immune regulation, autophagy, gut microbiota, blood-brain barrier integrity, and NLRP3 inflammasome-mediated pyroptosis in multiple sclerosis: potential clinical implications
Rituximab and IVIG added to plasma exchange improves the outcome of severe CNS demyelinating attacks: a retrospective study
Study Overview The study aimed to evaluate the effectiveness of combining rituximab and intravenous immunoglobulin (IVIG) therapy alongside plasma exchange in patients experiencing severe central nervous system (CNS) demyelinating attacks. CNS demyelinating conditions, such as multiple sclerosis and neuromyelitis optica, can lead to significant neurological impairment, necessitating prompt and effective treatment strategies. Through a retrospective… Read more: Rituximab and IVIG added to plasma exchange improves the outcome of severe CNS demyelinating attacks: a retrospective study
ISG15/ISGylation in central nervous system diseases: molecular mechanisms and therapeutic targeting
Molecular Mechanisms of ISG15/ISGylation ISG15, or interferon-stimulated gene 15, is a small ubiquitin-like modifier that plays a crucial role in the post-translational modification of proteins through a process known as ISGylation. This modification is similar to ubiquitination, where proteins are tagged for degradation, but ISGylation has unique functions and regulatory mechanisms. The ISG15 molecule is… Read more: ISG15/ISGylation in central nervous system diseases: molecular mechanisms and therapeutic targeting

Diagnostic and Prognostic Significance of the S100 Biomarker in Blast-related Closed Traumatic Brain Injury
CONCLUSION: S100 can be considered a useful biomarker for early grading of brain injury severity and outcome prediction in blast‑related closed TBI. Integration of S100 into multimodal diagnostic algorithms has the potential to improve stratification of patients, inform therapeutic decision‑making, and enhance outcomes in military and civilian populations exposed to blast trauma.
MEG Working Memory N-Back Task Revealed Functional Deficits in Children with Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) is a leading cause of sustained cognitive complaints in children. However, the TBI-related mechanisms underlying persistent cognitive symptoms including working memory (WM) dysfunction are not fully understood. Few pediatric studies of WM deficits in mTBI have taken advantage of the temporal and frequency resolution afforded by electromagnetic measurements. Using magnetoencephalography […]
Epidemiology of traumatic brain injury in a South African major trauma cohort
CONCLUSIONS: TBI represents a significant burden in South Africa's Western Cape. Within this head injury cohort, there are significant differences in injury characteristics and transport patterns. Mortality and neurofunctional recovery vary significantly across TBI severity but remain significantly worse for those with TBI even when controlling for potential confounders.
Reading Comprehension and Employment After Traumatic Brain Injury: Preliminary Findings From Clinical Practice
CONCLUSIONS: This preliminary analysis suggests reading comprehension may be an underassessed barrier to employment following TBI. The strong association with verbal comprehension indicates that language assessments routinely administered by speech-language pathologists may serve as screening tools for reading-related employment risk. Findings support incorporating reading assessment into cognitive-communication evaluations when vocational outcomes are rehabilitation priorities, although […]
List Length in Verbal and Nonverbal Memory Performance in Mild Traumatic Brain Injury
CONCLUSION: These findings highlight the heterogeneity of memory outcomes following mTBI and underscore the importance of tailored cognitive assessments that consider task complexity and memory load.

Related Posts

Leave a Comment Cancel Reply