Microwave ablation treatment for follicular nodular disease in DICER1 syndrome: a case report

February 27, 2026

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TREM2 in neurodegenerative diseases and acute neurological injuries: mechanisms to targeted therapies
Trem2 Function in Neurodegenerative Diseases TREM2, or Triggering Receptor Expressed on Myeloid Cells 2, plays a crucial role in the immune response of the central nervous system, particularly as it relates to neurodegenerative diseases. This protein is predominantly expressed on microglia, the resident immune cells of the brain, where it serves to regulate inflammation and… Read more: TREM2 in neurodegenerative diseases and acute neurological injuries: mechanisms to targeted therapies
Role of sRAGE in clinical heterogeneity and inflammation in endometriosis patients undergoing IVF; case-control study
Background and Rationale Endometriosis is a complex and often painful condition where tissue similar to the lining of the uterus grows outside the uterus. This condition affects a significant percentage of women of reproductive age and can lead to a variety of symptoms, including chronic pelvic pain, irregular menstruation, and difficulties in conceiving. The pathophysiology… Read more: Role of sRAGE in clinical heterogeneity and inflammation in endometriosis patients undergoing IVF; case-control study
Characterizing functional connectivity alterations in functional/ dissociative seizures using resting-state and naturalistic fMRI
Study Overview The research presents a comprehensive exploration of how functional connectivity changes in the brain occur in individuals experiencing functional or dissociative seizures, analyzed through the lens of resting-state and naturalistic functional Magnetic Resonance Imaging (fMRI). The goal of the study is to enhance the understanding of the neural mechanisms underlying these types of… Read more: Characterizing functional connectivity alterations in functional/ dissociative seizures using resting-state and naturalistic fMRI
Ferritin-ApoE nanocarrier for targeted therapy of neuromyelitis optica spectrum disorder in mice
Study Overview The investigation centered on the development and assessment of a specialized nanocarrier system combining ferritin and apolipoprotein E (ApoE) aimed at delivering targeted therapy for neuromyelitis optica spectrum disorder (NMOSD) in a mouse model. NMOSD is characterized by severe inflammation and demyelination of the central nervous system, which can lead to debilitating neurological… Read more: Ferritin-ApoE nanocarrier for targeted therapy of neuromyelitis optica spectrum disorder in mice
In situ generation of EBNA1 CAR-T cells eradicates antigen specific auto-immune B cells for multiple sclerosis treatment
Study Overview The research delves into the innovative approach of utilizing CAR-T cell therapy, specifically targeting the Epstein-Barr nuclear antigen 1 (EBNA1), to effectively manage multiple sclerosis (MS) by eradicating auto-reactive B cells. Multiple sclerosis is characterized by the immune system mistakenly attacking the central nervous system, leading to a spectrum of neurological disabilities. The… Read more: In situ generation of EBNA1 CAR-T cells eradicates antigen specific auto-immune B cells for multiple sclerosis treatment

Correction: Sekar et al. Concussion/Mild Traumatic Brain Injury (TBI) Induces Brain Insulin Resistance: A Positron Emission Tomography (PET) Scanning Study. Int. J. Mol. Sci. 2021, 22, 9005
In the original publication [...].
The Relationship Between Sociodemographic Factors and Mental Health Outcomes in Adolescents After a Sport-Related Concussion
CONCLUSIONS: Pediatric patients with an SRC reported modest postconcussion symptoms and mild-to-moderate mental health symptoms. Higher postconcussion symptom scores were linked with higher anxiety and depression levels, suggesting these symptoms tend to occur together. In contrast, a patient's race or household income was not a determinant of concussion symptomology or mental health outcomes.
GFAP and UCH-L1 for Ruling out Intracranial Lesions After Mild Traumatic Brain Injury: A Systematic Review and Meta-Analysis
Background: Patients with mild traumatic brain injury (mTBI) have a small but clinically relevant risk of intracranial injury (ICI), requiring timely detection. Computed tomography (CT) remains the diagnostic gold standard but is costly and exposes patients to ionising radiation. Combining blood-based biomarkers, glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), with clinical […]
Modulatory Role of Arbutin on Hepatic Inflammation and Apoptosis After Mild Repetitive Traumatic Brain Injury in Experimental Rats: Involvement of NGF/TrkA and IL-6/JAK2/STAT3 Immune Signaling Crosstalk
Repetitive traumatic brain injury (RTBI) can cause long-term complications, including persistent neuroinflammation, which can extend beyond the central nervous system, impacting various peripheral organs as liver. This study aimed to explore the neuroprotective and hepatoprotective effects of arbutin treatment in a rat model of mild RTBI (mRTBI), focusing on nerve growth factor (NGF)/tropomyosin receptor kinase […]
Characteristics and Clinical Outcomes Between Sport-Related and Non-Sport-Related Concussions in Youth Athletes
CONCLUSIONS: In high school athletes, non-SRCs were more common in female athletes and involved higher psychiatric and migraine history proportions. Non-SRCs were associated with broader symptom profiles and longer recovery, highlighting clinically meaningful differences. Findings underscore the need for tailored care strategies, including emotional and academic support, for athletes recovering from non-SRC.

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