Microwave ablation treatment for follicular nodular disease in DICER1 syndrome: a case report

February 27, 2026

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Recurrent blood-spitting as a somatic presentation of pediatric functional neurological disorder: a case report
Case Presentation A 10-year-old female presented to the emergency department with recurrent episodes of blood-spitting, which had been intermittent over the past month. The initial episode occurred suddenly while the patient was playing, resulting in a small amount of blood being expelled from her mouth, causing immediate distress and concern among her caregivers. The family… Read more: Recurrent blood-spitting as a somatic presentation of pediatric functional neurological disorder: a case report
Goal attainment scaling for patients with chronic low back pain receiving physical therapist care: a feasibility and reliability study
Background and Rationale Chronic low back pain (CLBP) is a prevalent condition that significantly impacts individuals’ quality of life, affecting physical functioning, mental health, and overall well-being. Traditional approaches to treatment often focus solely on alleviating pain; however, there is a growing recognition of the need to address broader functional and personal goals that patients… Read more: Goal attainment scaling for patients with chronic low back pain receiving physical therapist care: a feasibility and reliability study
Recurrent blood-spitting as a somatic presentation of pediatric functional neurological disorder: a case report
Study Overview This case report focuses on a rare manifestation of a pediatric functional neurological disorder through recurrent episodes of blood-spitting in a young patient. Functional neurological disorders (FND) are characterized by neurological symptoms that cannot be explained by organic disease. In children, these disorders present unique diagnostic challenges due to their varied symptoms and… Read more: Recurrent blood-spitting as a somatic presentation of pediatric functional neurological disorder: a case report
Brainstem Encephalitis With Conflicting Autoimmune and Infectious Markers: A Case Report
Case Presentation A 35-year-old female patient with no significant medical history presented to the hospital with a sudden onset of neurological symptoms. These manifestations included confusion, difficulty in speech, and motor deficits on the right side of her body. Family members reported that she had become increasingly disoriented over the span of 48 hours prior… Read more: Brainstem Encephalitis With Conflicting Autoimmune and Infectious Markers: A Case Report
Seronegative Chronic Relapsing Inflammatory Optic Neuropathy
Pathophysiology Seronegative Chronic Relapsing Inflammatory Optic Neuropathy (CRION) is primarily characterized by recurrent episodes of optic nerve inflammation without identifiable pathogenic autoantibodies. The underlying mechanisms contributing to the pathophysiology of CRION remain complex and multifactorial. It often presents following a pattern of relapses, where patients experience sudden vision loss that can improve with treatment but… Read more: Seronegative Chronic Relapsing Inflammatory Optic Neuropathy

The physiological effects of APOE genotype in healthy young/middle-aged individuals
The apolipoprotein E ε4 (APOE4) allele is a risk factor for cardiovascular disease and for multiple neurodegenerative diseases, most notably Alzheimer's disease (AD). However, in healthy infants to adults, the encoded apolipoprotein E protein plays a role in many physiological functions, in both the periphery and in the brain, which can help us understand the […]
The positive predictive value of ICD-10-AM S06.0~ concussion codes for mild traumatic brain injury
CONCLUSION: There are limitations to using ICD-10-AM concussive injury codes to identify mTBI in ED settings, and patient characteristics influence coding accuracy. Reconsideration of current ED coding practices, including exploration of alternative models that reduce clinician burden and improve coding accuracy, is recommended.Implications for health information management practice:The introduction of electronic medical records provides an […]
Serum interleukin-6 as a neuroinflammatory biomarker across the spectrum of neurological disorders: a large-scale retrospective cohort study of 6,465 individuals
CONCLUSION: In this large-scale cohort study, we demonstrate that serum IL-6 is a neuroinflammatory biomarker with robust efficacy for screening acute brain injury from healthy status. Its clinical interpretation requires age- and sex-stratified reference intervals, and it holds potential as a preliminary screening indicator for acute neurological conditions in specific clinical settings. The diagnostic utility […]
Diagnostic Accuracy of Plasma Biomarkers for Mild Traumatic Brain Injury in Older Adults
CONCLUSIONS AND RELEVANCE: In this cross-sectional study of older adults presenting within 72 hours of injury, the plasma GFAP concentration demonstrated excellent diagnostic accuracy for mTBI. GFAP was elevated in the majority of clinically suspected mTBI cases using age- and sex-adjusted thresholds, supporting its potential to improve diagnostic certainty in mTBI, particularly in diagnostically ambiguous […]
Sports-related concussion laws in the United States in children and adolescents: an updated cross-sectional review of state statutes
CONCLUSIONS: State concussion laws now universally mandate education, removal, and clearance before return, yet variability in coach training, return-to-play protocols, and cognitive testing exists. Aligning legislation with evidence-based standards is needed to ensure consistent protection for young athletes across the country.

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