Microwave ablation treatment for follicular nodular disease in DICER1 syndrome: a case report

February 27, 2026

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Does Hypoxic Burden Better Explain Sex Differences in Functional Impairments Than Apnoea-Hypopnoea Index in Obstructive Sleep Apnoea
Hypoxic Burden and Sex Differences Research has indicated that obstructive sleep apnea (OSA) presents differently in males and females, and an increasingly important aspect of this discrepancy is hypoxic burden. Hypoxic burden refers to the amount and duration of oxygen deprivation experienced during sleep due to apneic events. Studies have shown that women often report… Read more: Does Hypoxic Burden Better Explain Sex Differences in Functional Impairments Than Apnoea-Hypopnoea Index in Obstructive Sleep Apnoea
Neuromyelitis optica presenting with mammillary body and cervicomedullary lesions after severe hyponatremia mimicking osmotic demyelination syndrome
Study Overview This research investigates a rare case of neuromyelitis optica (NMO), a serious autoimmune disease affecting the central nervous system, particularly the optic nerves and spinal cord. The focus is on patients who experience this condition following severe hyponatremia, a state characterized by low sodium levels in the blood, which can lead to serious… Read more: Neuromyelitis optica presenting with mammillary body and cervicomedullary lesions after severe hyponatremia mimicking osmotic demyelination syndrome
Roles of cerebrospinal fluid metabolites in neuromyelitis optica spectrum disorder: Insights from Mendelian randomization
Study Overview The research investigates the roles of metabolites present in cerebrospinal fluid (CSF) within the context of neuromyelitis optica spectrum disorder (NMOSD). NMOSD is an autoimmune condition predominantly characterized by inflammation and demyelination of the optic nerve and spinal cord. This study employs Mendelian randomization—a robust statistical approach that strengthens causal inference— to explore… Read more: Roles of cerebrospinal fluid metabolites in neuromyelitis optica spectrum disorder: Insights from Mendelian randomization
Association of incomplete device apposition with stroke recurrence after patent foramen ovale closure
Study Overview The research investigates the relationship between incomplete apposition of closure devices used during patent foramen ovale (PFO) closure and the recurrence of strokes in patients. PFO is a common cardiac anomaly believed to contribute to the risk of cryptogenic strokes, particularly in younger individuals. Standard treatment often involves the use of percutaneous closure… Read more: Association of incomplete device apposition with stroke recurrence after patent foramen ovale closure
Interactive Effects of Plasma Alzheimer Disease Biomarkers and White Matter Hyperintensities on Cognitive Decline and Clinical Progression in Nondemented Adults
Study Overview The research investigates the interplay between plasma biomarkers indicative of Alzheimer’s disease and the presence of white matter hyperintensities in the brains of cognitively healthy adults. The premise is that these biomarkers and hyperintensities may contribute to cognitive decline, even among those who do not exhibit overt dementia symptoms. Tracking this relationship is… Read more: Interactive Effects of Plasma Alzheimer Disease Biomarkers and White Matter Hyperintensities on Cognitive Decline and Clinical Progression in Nondemented Adults

Evaluating clinical associations of immediate post-traumatic headache: a prospective multicenter study
CONCLUSIONS: An association model based on 9 routine ED variables identified several clinical and specific trauma features strongly associated with immediate PTH in mild head trauma patients. These findings highlight important early prognostic factors and maintain statistical stability; however, external validation is required before widespread clinical application.
Region-Specific Brain Imaging Correlates of Repetitive Head Impact Exposure in Nonconcussed High School Football Players
Repetitive, nonconcussive head impacts in collision sports are associated with lasting neurophysiological effects. This study investigates region-specific changes in neocortical mean diffusivity (MD) and resting-state functional magnetic resonance imaging (fMRI) power spectral density (fMRI-PSD) that correlate with cumulative nonconcussive linear risk-weighted exposure (RWE-Lin) sustained over one high school football season. Pre- to postseason percent changes […]
Lifetime Concussions and Head Impact Exposure During Collegiate Athletics: A CARE Consortium Study
CONCLUSIONS: These findings suggest that RHIs or lifetime number of concussions have no clinical consequences during university athletics. Further longitudinal investigations are warranted to evaluate brain health later in life.
Traumatic brain injury in patients with mechanical heart valves on lifelong anticoagulation: incidence, management, and outcomes of intracranial hemorrhage
CONCLUSIONS: Intracranial hemorrhage following TBI is common in anticoagulated mechanical valve patients and is associated with a lower rate of composite good outcome compared to TBI without hemorrhage (66.7% vs. 90.0%). Among haemorrhagic TBI events, composite good outcomes were numerically more frequent with conservative than with surgical management (71.4% vs. 55.6%); however, given the small […]
Pediatric Repetitive Mild Traumatic Brain Injury Elicits T Cell-Mediated Neuroinflammation
Pediatric repetitive mild traumatic brain injury (rmTBI) is a major public health concern with links to chronic cognitive dysfunction. Neuroinflammation represents a significant maladaptive outcome after rmTBI. Persistent innate and adaptive immune cell responses can lead to neurodegeneration and deficits in brain development. Therefore, a deeper understanding of the early dynamics of peripheral immune cell […]

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