Splitting FND: Differences in targeted therapies for functional movement disorders and functional seizures

February 20, 2026

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Inpatient Neurorehabilitation Benefits Patients with Functional Neurological Disorder: A Single Centre Study
Study Overview The study aims to investigate the effects of inpatient neurorehabilitation on patients diagnosed with Functional Neurological Disorder (FND), a condition characterized by neurological symptoms that cannot be attributed to a structural malfunction in the nervous system. Patients affected by FND often experience seizures, movement disorders, and other symptoms that can significantly impair their… Read more: Inpatient Neurorehabilitation Benefits Patients with Functional Neurological Disorder: A Single Centre Study
Comorbidities and Outcomes in People With Functional Neurological Disorder
Comorbidity Patterns Comorbidity, or the presence of one or more additional conditions co-occurring with a primary condition, is a significant factor in understanding functional neurological disorder (FND). Various studies have highlighted the prevalence of different psychiatric and physical health issues among patients with FND, indicating that these individuals often present with a complex interplay of… Read more: Comorbidities and Outcomes in People With Functional Neurological Disorder
Inappropriate prescribing of antiseizure medications in people with functional seizures: A call to action
Understanding Functional Seizures Functional seizures, also known as psychogenic nonepileptic seizures (PNES), represent a complex interaction of psychological and neurological factors, breaking the traditional perception of seizures as strictly pathological neurological events. These seizures often mimic epilepsy but arise from psychological distress rather than electrical disruptions in the brain. This distinction is critical as it… Read more: Inappropriate prescribing of antiseizure medications in people with functional seizures: A call to action
Characteristics of the upper trapezius muscle in patients with chronic shoulder impingement syndrome: a comparative study
Study Overview The investigation focused on the upper trapezius muscle in individuals suffering from chronic shoulder impingement syndrome, a common condition associated with pain and functional limitations in the shoulder. The research aimed to characterize differences in muscle properties between patients diagnosed with this syndrome and a control group without any shoulder issues. Through a… Read more: Characteristics of the upper trapezius muscle in patients with chronic shoulder impingement syndrome: a comparative study
Inpatient Neurorehabilitation Benefits Patients with Functional Neurological Disorder: A Single Centre Study
Patient Population The study focused on a specific group of individuals diagnosed with Functional Neurological Disorder (FND), a condition characterized by physical symptoms that cannot be explained by medical or neurological conditions. This patient population was drawn from a single center, allowing for the collection of comprehensive and controlled data. Participants included both males and… Read more: Inpatient Neurorehabilitation Benefits Patients with Functional Neurological Disorder: A Single Centre Study

Neuropathological and Behavioral Effects of Mild Traumatic Brain Injury at High Altitude
OBJECTIVE: In lowlanders, ascent to and prolonged stay at high altitude (HA) can trigger maladaptive changes in neurovascularization, immune function, and hippocampal-dependent cognitive impairment. Mild traumatic brain injury (mTBI) induces similar neuropathological and behavioral alterations. The primary objective of this study was to characterize the impact of mTBI at HA on behavioral and neuropathological outcomes […]
Repetitive transcranial magnetic stimulation for neuropathic pain and neuropsychiatric sequelae in traumatic brain injury: A meta-analysis and trial sequential analysis
CONCLUSION: rTMS may provide short-term benefits in reducing neuropathic pain and potentially for post-concussive symptoms in patients with TBI. More studies are needed to confirm the benefits of using rTMS for post-concussive and neuropsychiatric symptoms.
The long march towards testing the adenosine receptor agonism hypothesis for human cerebroprotection: The story of the A1R/A3R receptor agonist AST-004
AST-004 is an adenosine A(1)R/A(3)R agonist and promising cerebroprotectant currently in Phase II clinical development. Clinical evaluations have been initiated in concussion, with trials in preparation for mild complicated traumatic brain injury (TBI) and acute ischemic stroke (AIS). AST-004 was discovered as the result of basic research on the P2Y(1)R-activated homeostatic roles of astrocytes in […]
Blood-Based Biomarkers and Cognitive-Behavioral Assessment in Mild Traumatic Brain Injury: Current Evidence and Clinical Perspectives
Mild traumatic brain injury (mTBI) comprises the majority of all traumatic brain injuries, but clinical evaluation remains challenging because conventional neuroimaging cannot adequately detect subtle structural abnormalities or explain functional disturbances. Blood-based biomarkers have been studied as indicators of tissue injury. They may help reduce unnecessary computed tomography scans and predict unfavorable outcomes. However, biomarkers […]
Shifting the Paradigm: Redefining Our Approach to Mild Traumatic Brain Injury
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