Tag:

human brain

Dementia
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids

by myneuronews September 17, 2025

by myneuronews September 17, 2025

Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Mechanisms of motor dysfunction in functional neurological disorder: A narrative review

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a range of neurological symptoms …

Read more

0 Facebook Twitter Pinterest Email
Dementia
High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

by myneuronews August 22, 2025

by myneuronews August 22, 2025

Study Overview The research focused on improving the delivery of bispecific antibodies to the brain. …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview The research conducted aimed to investigate how machine learning can be utilized to …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Analysis of biased allelic enhancer activity of schizophrenia-linked common variants

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Biased allelic enhancer activity in schizophrenia Recent findings have highlighted the complexity of genetic factors …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Erratum: Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview The research presented focuses on the development and validation of an advanced animal …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Sex-dependent blood-brain barrier alterations following repeated mild blast traumatic brain injury at varying inter-injury intervals

by myneuronews June 1, 2025

by myneuronews June 1, 2025

Study Overview The investigation focused on the impact of repeated mild blast traumatic brain injuries …

Read more

0 Facebook Twitter Pinterest Email

Prevalence of depression, anxiety, fatigue, and headache before and after long COVID onset: a case-control study in the total population of Region Stockholm
Study Overview The investigation centered on the prevalence rates of common mental and physical health…
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum
Study Overview The research focused on understanding the intricate relationship between brain network connectivity and…
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients
Study Summary The recent study presents an extensive analysis of functional seizure disorder, conducted through…
Phenotyping Functional Gait Disorder: An Exploratory Analysis of Existing Frameworks
Phenotyping Functional Gait Disorder Functional Gait Disorder (FGD) represents a unique challenge in the field…
Diagnosis and treatment of functional visual disorder
Understanding Functional Visual Disorder Functional Visual Disorder (FVD) is a condition that presents a unique…

Profiles of cold executive function performance among pediatric acquired brain injury
CONCLUSIONS: Distinct executive function profiles were observed across ABI subtypes, with PAS associated with the most pervasive impairments, TBI with selective deficits, and BT with targeted planning difficulties. These findings highlight the importance of tailored cognitive rehabilitation strategies based on ABI subtype.
Longitudinal neurocognitive outcomes in children with mild traumatic brain injury: An ABCD cohort analysis
CONCLUSIONS: The findings highlight the importance of accounting for pre-injury differences when evaluating neurocognitive outcomes following pediatric mTBI. Neurocognitive differences within a year post-injury may be more related to pre-existing individual factors rather than the injury itself, underscoring the need for a comprehensive approach in studying pediatric mTBI.
Fear Avoidance after Concussion Tool (FACT): patient-reported outcome measure development and content validation
CONCLUSION: The FACT has been developed to evaluate fear avoidance behaviour following concussion and has content validity. Future research should evaluate other measurement properties before implementation.
Spare the brain: female football players' perspectives of heading the ball, concussion knowledge and attitudes. A qualitative study
The aim of this study was to explore female football (soccer) players' perspectives of heading the ball, and perceived header injury risk. A qualitative approach was undertaken using reflexive thematic analysis. Focus groups and individual interviews were conducted using a semi-structured interview guide. Participants also completed a survey containing a validated concussion knowledge and attitudes […]
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
Traumatic brain injury (TBI) constitutes a major global public health concern associated with substantial mortality and long-term disability, while its diagnostic approaches and underlying pathophysiological mechanisms remain to be fully elucidated. In this study, we conducted longitudinal metabolomic profiling of cerebrospinal fluid (CSF) from 23 TBI patients (9 mild, 14 severe) and 5 uninjured controls […]