Tag:

human brain

Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids

by myneuronews September 17, 2025

by myneuronews September 17, 2025

Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Mechanisms of motor dysfunction in functional neurological disorder: A narrative review

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a range of neurological symptoms …

Read more

0 Facebook Twitter Pinterest Email
Dementia
High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

by myneuronews August 22, 2025

by myneuronews August 22, 2025

Study Overview The research focused on improving the delivery of bispecific antibodies to the brain. …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview The research conducted aimed to investigate how machine learning can be utilized to …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Analysis of biased allelic enhancer activity of schizophrenia-linked common variants

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Biased allelic enhancer activity in schizophrenia Recent findings have highlighted the complexity of genetic factors …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Erratum: Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview The research presented focuses on the development and validation of an advanced animal …

Read more

0 Facebook Twitter Pinterest Email

Prevalence of Traumatic Brain Injury in Detained Youth: Associations With Aggression, Violent Charges, and Behavioral Infractions
CONCLUSIONS: TBI is common among detained youth and is selectively associated with elevated physical aggression. Routine TBI screening at intake and interventions targeting impulse control and emotion regulation may improve outcomes for this high-risk population.
Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review
CONCLUSION: The main challenge during the analysis was methodological, population, and statistical heterogeneity, which required not only the use of a random effects model but also active search and exclusion of some sources. However, despite several limitations, the internal consistency and absence of contradictions in the analysis results demonstrated the robustness of the evidence obtained. […]
Relationships between vestibular dysfunction and cognitive performance in military veterans with mild to moderate TBI
Objective: Vestibular dysfunction is common following mild-to-moderate traumatic brain injury (TBI) and impacts quality of life. However, little is known regarding the persistence and stability of vestibular symptoms over time and their effects on cognition. This study examined self-reported vestibular symptoms 1 to 2 years following mild-to-moderate TBI in a Military/Veteran cohort. We further evaluated […]
Within-Person Score Distribution Measures as Performance Validity Indicators in Service Members and Veterans with and without History of Mild Traumatic Brain Injury
CONCLUSIONS: OTBM and ABN demonstrated strong potential for use as embedded PVTs with excellent classification accuracy. CV displayed lower classification accuracy with group differences primarily due to changes in mean performance rather than increased dispersion. Further development and cross-validation of WPSD-based PVTs is warranted in civilian samples.
Development of a Fall-Specific Impact Testing Method to Evaluate Safety Helmet Performance and Injury Risk
CONCLUSIONS: Type II helmets offer substantial benefits in head protection compared to Type I models for oblique fall-related impacts. By including both skull fracture and concussion risk in the STAR score, the proposed methodology can differentiate high and low-performing safety helmets.