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human brain

Traumatic brain injury
Corrigendum to ‘Anti-Inflammatory, Antioxidant and Neuroprotective Effects of Niacin on Mild Traumatic Brain Injury in Rats.’

by myneuronews January 19, 2026

by myneuronews January 19, 2026

Study Overview The investigation was centered around evaluating the therapeutic contributions of niacin, a form …

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Traumatic brain injury
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits

by myneuronews January 14, 2026

by myneuronews January 14, 2026

Study Overview This research investigates the roles of specific biomarkers—ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial fibrillary …

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Traumatic brain injury
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview This research explores the phenomenon of ferroptosis, a form of regulated cell death …

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Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Dementia
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids

by myneuronews September 17, 2025

by myneuronews September 17, 2025

Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease …

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Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …

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Dementia
High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

by myneuronews August 22, 2025

by myneuronews August 22, 2025

Study Overview The research focused on improving the delivery of bispecific antibodies to the brain. …

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Traumatic brain injury
Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview The research conducted aimed to investigate how machine learning can be utilized to …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia
Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia…
Are symptoms clustered into latent classes in pediatric functional neurological disorder?
Symptoms Clustering in Pediatric Functional Neurological Disorder Pediatric functional neurological disorder (FND) presents a complex…
An e-Delphi approach to develop a patient-reported outcome measure to assess functional/dissociative seizures severity
Study Overview In recent years, the growing recognition of the impact of functional/dissociative seizures on…
Diagnostic challenges in Burkitt’s lymphoma with skull base and paravertebral involvement, and hearing loss: a case report
Study Overview This case report focuses on Burkitt’s lymphoma, a highly aggressive type of non-Hodgkin…
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of…

miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
CONCLUSION: miRNAs 1246, 944, and 151a-3p may be concussion biomarkers unaffected by aerobic exercise. miR-26b-5p, associated with concussion and exercise volume, may be a useful biomarker to monitor adherence to exercise prescriptions for SRC recovery.
Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?
Creatine is an important regulator of brain bioenergetics, yet the efficacy of creatine supplementation (CrS) in the brain remains largely unknown. Measurement of brain creatine using proton (¹H) and phosphorus (³¹P) magnetic resonance spectroscopy is highly sensitive to voxel placement, signal quality, analysis pipelines, and reporting conventions which can obscure the detection of biological responses […]
Concussion recovery time, return-to-play protocols, and mandated sit-out periods among adult amateur contact field sports: A systematic review
CONCLUSION: Recovery time following concussion in contact sports should be interpreted in light of sport type, mandated sit-out policies, and RTP protocols. Empirical evidence should drive decisions in RTP protocols and sit-out periods, which are currently inconsistent between sports.
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H(2)S-dependent S-sulfhydration of CTSD
CONCLUSION: Snapin promotes mTBI-induced neuronal PANoptosis by disrupting the H(2)S/CTSD pathway through specific binding with CBS. Therapeutic strategies targeting Snapin, restoring H(2)S homeostasis, or inhibiting CTSD activation may significantly alleviate neurological impairment and neuroinflammation post-mTBI, highlighting novel therapeutic avenues for mTBI treatment.
Prevalence of post-traumatic hypopituitarism in active-duty service members receiving comprehensive care for traumatic brain injury (TBI) and psychological health: A military mild TBI cohort study
Objective: The prevalence of neuroendocrine dysfunction (NED) following mild traumatic brain injury (mTBI) remains obscure, with widely varying prevalence estimates. This study aimed to determine prevalence of NED among central hypogonadism, central hypothyroidism, and growth hormone deficiency (GHD) in active-duty military service members (SMs) receiving comprehensive TBI and psychological health care and characterize TBI burden, […]