Tag:

neuroinflammation

Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Microglia are the primary immune cells of the central nervous system, …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation and Its Consequences Recent research has highlighted the significant role of …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Their Role in Parkinson’s Disease Microglia are specialized immune cells in the central …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Microglia, the resident immune cells of the brain, play a crucial …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Perturbations in gut microbiota in autism spectrum disorder: a systematic review

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Gut Microbiota Alterations in Autism The gut microbiota consists of a diverse community of microorganisms …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Pathophysiology Microglia, the resident immune cells of the central nervous system, …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Sex-dependent blood-brain barrier alterations following repeated mild blast traumatic brain injury at varying inter-injury intervals

by myneuronews June 1, 2025

by myneuronews June 1, 2025

Study Overview The investigation focused on the impact of repeated mild blast traumatic brain injuries …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
A 2025 update on treatment strategies for the Alzheimer’s disease spectrum

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Treatment Approaches The treatment landscape for Alzheimer’s disease has evolved considerably, reflecting a multifaceted …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Biomarkers in Traumatic Brain Injury Biomarkers are measurable indicators in the body that can reflect …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Combination Therapy of Estrogen and Progesterone Attenuates Behavioral Impairments and Autophagy via circLrp1b/miR-27a-3p/Dram2 Pathway After Traumatic Brain Injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Study Overview The research investigates the effects of combination therapy involving estrogen and progesterone in …

Read more

0 Facebook Twitter Pinterest Email

Subcutaneous Botulinum Toxin Type-A Injections for the Treatment of Central Neuropathic Pain in a Patient With Multiple Sclerosis – A Case Report
Study Overview This case report examines the application of subcutaneous injections of botulinum toxin type…
Homozygous COQ9 mutation: a new cause of potentially treatable hereditary spastic paraplegia
Study Overview The research investigates the role of homozygous mutations in the COQ9 gene as…
Trends in acute care of cerebrovascular events- a joinpoint analysis with German hospital data from 2000 to 2021
Cerebrovascular Event Trends The prevalence and incidence of cerebrovascular events, commonly known as strokes, have…
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine
Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to…
Targeting cognitive aging with curcumin supplementation: A systematic review and meta-analysis
Study Overview The systematic review and meta-analysis centered on curcumin supplementation aimed to investigate its…

Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods
Military service members (SMs) and veterans who have sustained one or more concussions during their service have significantly higher rates of persistent depressive symptoms and suicidality compared to non-injured peers. Despite over 500,000 SMs who have sustained concussions, there are currently no Level I evidence-based treatments for improving depressive symptoms associated with concussion. Accelerated intermittent […]
Dietary Intake of n-3 Polyunsaturated Fatty Acids Prior to a Mild Traumatic Brain Injury Demonstrates a Dose-Response Effect for Neuroprotective Benefits in Male C57BL/6 Mice
CONCLUSIONS: Overall, these results show that dietary n-3 PUFA confer neuroprotective benefits in mice resulting in significantly improved functional outcomes. This work is relevant to clinical practitioners, athletes, and the general population who aim to support their neurological health through dietary or supplementary n-3 PUFA.
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared to Orthopedic Injury
CONCLUSIONS AND RELEVANCE: BDNF DNAm appears to differ in children with TBI vs OI, particularly in the acute period. BDNF DNAm differences may reflect early biological responses that are specific to TBI.
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition
Mild repetitive head injury is a serious health problem with long-term negative consequences. Changes in brain neurobiology were assessed with MRI in a model of head injury designed to reflect the human experience. Rats were maintained on a reverse light-dark cycle and head impacted daily at 24 h intervals over three days while fully awake […]
Microstructural Damage Progression in the Pia-Arachnoid Complex
Traumatic brain injury is a leading cause of death and disability worldwide, with mild traumatic brain injury comprising the majority of cases. The pia-arachnoid complex (PAC), located at the brain-skull interface, plays a critical role in brain mechanics during head impacts, yet its response to mechanical loading is understudied. This study investigates the progression of […]