Tag:

neuroinflammation

Traumatic brain injury
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Study Overview The research focuses on the development of a specialized apparatus designed to replicate …

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Functional neurological disorders
AAV-based gene therapy ameliorates neurological deficits in a mouse model of childhood-onset neurodegeneration with cerebellar atrophy (CONDCA)

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Study Summary The study investigates the efficacy of adeno-associated virus (AAV)-based gene therapy in a …

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Traumatic brain injury
Knockout of indoleamine 2,3-dioxygenase 1 gene expression improves depressive and anxiety-like phenotypes in a murine model of mild traumatic brain injury

by myneuronews August 3, 2025

by myneuronews August 3, 2025

Study Overview The research investigates the effects of knocking out the expression of the indoleamine …

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Dementia
Environmental aluminum exposure and Alzheimer’s disease risk: Evidence from a systematic review and meta-analysis

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Study Overview The investigation into the potential link between environmental aluminum exposure and the risk …

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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Traumatic brain injury
Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Historical Context of Neurological Disorders The understanding of neurological disorders in Boxers has evolved significantly …

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Dementia
Examination of age- and sex-related changes in protein expression within the hippocampus and prefrontal cortex during withdrawal from a subchronic history of binge-drinking in C57BL/6J mice

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Study Overview This study investigates the impact of binge-drinking behavior on protein expression in specific …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging findings in Wilson’s disease reveal significant alterations in brain …

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Traumatic brain injury
Microglial depletion and repopulation differentially modulate sleep and inflammation in a mouse model of traumatic brain injury

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Study Overview This research investigates the complex relationship between microglial cells, sleep patterns, and inflammation …

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Long-term neurological and psychiatric complications and vocational outcome after cerebral venous sinus thrombosis
Patient Characteristics The demographic profile of patients who experience cerebral venous sinus thrombosis (CVST) provides…
Reply to “Clarifying the Moderating Role of Socioeconomic Status on Amyloid-Related Gray Matter Atrophy”
Study Overview This study addresses the complex interactions between socioeconomic status (SES) and the neurobiological…
A Scoping Review of Measures Used to Assess Stress-Related Motor Dysfunction in Functional Movement Disorder
Assessment Methods Overview Assessing stress-related motor dysfunction in individuals with functional movement disorder (FMD) encompasses…
Hysterical disorders in patients with hematological diseases
Prevalence of Hysterical Disorders in Hematological Patients The intersection of hematological diseases and hysterical disorders…
Indigenizing paediatric concussion injury prevention
Indigenous Perspectives on Concussion Understanding concussion within Indigenous communities requires a deep appreciation of cultural…

IL6 in Combination with Either NfL, NTproBNP, or GFAP to Safely Discharge Children with Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) in children is a public health concern resulting in one of the main causes of pediatric emergency department (PED) visits. However, the acute care of mTBI patients remains challenging due to the limited use of specific and safe diagnostic tools. The objective of the study was to evaluate the performance […]
What traditional neuropsychological assessment got wrong about mild traumatic brain injury. III: the added value of advanced neuroimaging
CONCLUSIONS: Characterizations from traditional neuropsychological measures as independent tests indicating no lasting sequelae from mTBI, especially after three-months post-injury from mTBI need to be viewed within the context of what advanced neuroimaging can demonstrate. Future directions involving the integration of advanced neuroimaging developments applicable to the mTBI patient are reviewed, especially when integrated with neuropsychological […]
Preparing for Potential Health and Safety Risks at the Olympic Games: Scoping Review
CONCLUSIONS: A critical summary of studies of illness, injury, and terrorist attacks at previous Olympic Games is important for injury and terrorism prevention at major sporting events such as the Olympic Games. Surveillance methods require improvements in surveillance technology, data sharing, and privacy protection.
Infographic. Keep an eye on vision after concussion-screening tool and procedure for the two most common concussion-related vision disorders: convergence insufficiency and accommodative insufficiency
No abstract
Plumbagin Alleviates Mild Traumatic Brain Injury-Induced Obsessive-Compulsive Disorder in Mice by Inhibiting nNOS and Augmenting Cortico-Striatal Serotonin Levels
Increased nitric oxide activity in the medial prefrontal cortex (mPFC) and striatum plays a key role in the pathogenesis of obsessive-compulsive disorder (OCD) by lowering serotonin contents and triggering neurodegeneration. Since molecular docking analysis revealed plumbagin as a potent inhibitor of neuronal nitric oxide synthase (nNOS) enzyme, this study aims to investigate the ameliorative potential […]