Tag:

neuroinflammation

Traumatic brain injury
A Modified Repetitive Closed Head Injury Model Inducing Persistent Neuroinflammation and Functional Deficits Without Extensive Cortical Tissue Destruction

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Study Overview This research explores the effects of repeated mild traumatic brain injuries (mTBIs) on …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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Traumatic brain injury
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Overview of Posttraumatic Headache Posttraumatic headache (PTH) is a prevalent and often debilitating disorder that …

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Traumatic brain injury
AQP4 in cerebrospinal fluid correlates with severity and prognosis in moderate to severe traumatic brain injury

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Background and Rationale Traumatic brain injury (TBI) is a significant public health concern, often resulting …

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Traumatic brain injury
The Effect of Mucuna pruriens on Depression-like Behavior Induced by a Mild Traumatic Brain Injury in Rats Is Associated with a Decrease in Brain Nitrite and Nitrate Levels

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Study Overview The research investigates the impact of Mucuna pruriens, a tropical legume known for …

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Traumatic brain injury
Post-Traumatic Epilepsy After Mild and Moderate Traumatic Brain Injury: A Narrative Review and Development of a Clinical Decision Tool

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Study Overview This review article examines the complex relationship between post-traumatic epilepsy (PTE) and mild …

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Dementia
Mitochondrial dysfunction, a new marker warning of neuropsychiatric disorder risk: evidence from genetics and epidemiology

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Mitochondrial Dysfunction and Neuropsychiatric Disorders Mitochondria, often referred to as the powerhouses of the cell, …

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Dementia
Apathy and cognitive decline as the first presentation of SLE-associated vascular dementia: a case report

by myneuronews October 20, 2025

by myneuronews October 20, 2025

Case Presentation A 45-year-old woman, previously healthy with no history of psychiatric or neurological disorders, …

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Traumatic brain injury
Understanding concussion in myalgic encephalomyelitis/chronic fatigue syndrome: Findings from the 2023 National Health Interview study

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Concussion and Myalgic Encephalomyelitis Concussion is a type of traumatic brain injury that can have …

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Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis
Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in…
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective
Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders…
DCPat-XFE: an explainable EEG model for psychogenic nonepileptic seizure detection
Study Summary The study presents the DCPat-XFE model, designed to enhance the detection of psychogenic…
Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
Study Overview The focus of this scoping review is to explore the prevalence of vestibular…
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
Study Overview The article investigates the relationship between engagement in sports and physical activities and…

Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint
Transcranial direct current stimulation (tDCS) for painless, non-invasive brain stimulation is a promising approach to enhance recovery after stroke. However, the precise molecular and cellular mechanisms underlying the effects of tDCS remain unclear, impeding its use in humans and necessitating research in experimental animals. Unlike humans, who receive tDCS fully awake, experimental models of tDCS […]
Artificial Intelligence in Traumatic Brain Injury: A Systematic Review of Prognostic, Diagnostic, and Monitoring Applications
Traumatic brain injury (TBI) remains a leading cause of death and disability worldwide, with outcomes that are highly heterogeneous and difficult to predict using conventional clinical tools. Artificial intelligence (AI) has emerged as a promising approach to enhance diagnosis, prognostication, and management of TBI across diverse care settings. Following PRISMA guidelines, a comprehensive search of […]
A study on the association of apolipoprotein E with oxidative stress markers, neurological function, and cognitive impairment following traumatic brain injury
CONCLUSION: ApoE exhibits an injury-severity-dependent increase during the early stage of TBI, and its levels are closely associated with oxidative stress imbalance and cognitive impairment. These findings suggest that ApoE may play a critical role in both the pathological progression and neural repair following TBI.
A comprehensive review on adaptive plasticity and recovery mechanisms post-acquired brain injury
Adaptive plasticity, the brain's ability to reorganize and form new neural connections after injury, is crucial for recovery following acquired brain injury (ABI). This process involves axonal sprouting, dendritic remodeling, and neurogenesis, which restore neural connections and compensate for lost functions. While neuroinflammation and reactive astrocytes aid tissue repair, optimizing these responses to minimize secondary […]
Sex differences in fixational eye movements following concussion
Recent research supports impairments in fixational eye movements (FEMs), small motions of the eye that occur during periods when gaze is maintained on a fixed target, as an objective biomarker of concussion. Preliminary work has demonstrated that fixational saccades are larger following a concussion; however, sex differences in FEMs and fixational saccades have not been […]