Altered microstate dynamics in Functional Neurological Disorder

February 26, 2026

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Functional (Dissociative) Narcolepsy: A Case Report and Literature Review
Case Presentation A 29-year-old male patient presented to the clinic with an unusual history of excessive daytime sleepiness, episodes of cataplexy characterized by muscle weakness triggered by emotional stimuli, and hypnagogic hallucinations. These symptoms began four years prior and had progressively worsened despite attempts to manage them with various lifestyle adjustments. His medical history was… Read more: Functional (Dissociative) Narcolepsy: A Case Report and Literature Review
Safety of short-term non-steroidal anti-inflammatory drug use in the postoperative setting in paediatric patients with chronic kidney disease: protocol for a randomised, placebo-controlled trial
Study Overview The research aims to investigate the safety of short-term use of non-steroidal anti-inflammatory drugs (NSAIDs) in children with chronic kidney disease (CKD) after surgical procedures. This cohort is particularly vulnerable, as CKD can predispose patients to various complications, especially regarding pain management and medication tolerance. The goal is to evaluate whether NSAIDs can… Read more: Safety of short-term non-steroidal anti-inflammatory drug use in the postoperative setting in paediatric patients with chronic kidney disease: protocol for a randomised, placebo-controlled trial
Functional (Dissociative) Narcolepsy: A Case Report and Literature Review
Study Overview This research investigates the phenomenon of functional (dissociative) narcolepsy, which is characterized by episodes of excessive daytime sleepiness and cataplexy that occur without the traditional neurobiological underpinnings of narcolepsy. Instead of arising from physiological abnormalities, these symptoms may be linked to psychosocial factors that influence a person’s consciousness and behavior. The case report… Read more: Functional (Dissociative) Narcolepsy: A Case Report and Literature Review
Case Report: Gait training using a wearable ankle-exoskeleton in a pediatric patient with Guillain-Barré syndrome
Study Overview This case report details the utilization of a wearable ankle-exoskeleton for gait training in a pediatric patient diagnosed with Guillain-Barré syndrome (GBS), a neurological condition characterized by rapid-onset muscle weakness due to the immune system mistakenly attacking the peripheral nervous system. GBS can lead to significant complications, including prolonged immobility and, in some… Read more: Case Report: Gait training using a wearable ankle-exoskeleton in a pediatric patient with Guillain-Barré syndrome
Minocycline ameliorates CNS autoimmunity through restraint of CD4+CD11bc+ cells
Study Overview In recent research, the efficacy of minocycline in treating central nervous system (CNS) autoimmunity has gained attention. The study was designed to investigate the mechanisms through which minocycline exerts its therapeutic effects, particularly focusing on its impact on specific immune cell populations. Autoimmune diseases affecting the CNS, such as multiple sclerosis, often involve… Read more: Minocycline ameliorates CNS autoimmunity through restraint of CD4+CD11bc+ cells

Chronic Hyponatremia Following Mild Traumatic Brain Injury: A Case of Persistent Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in a Young Adult
Hyponatremia is a well-recognized complication of traumatic brain injury (TBI), most commonly resulting from syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting (CSW) syndrome. While SIADH is frequently described following moderate to severe TBI, persistent SIADH after mild TBI is rare and has been infrequently reported. A 25-year-old man was admitted to […]
10 Years of Youth Sport Concussion Reporting in Missouri
Concussions in high school athletics are increasingly studied as a public health issue. Little is known about sport-related concussion among Missouri high school student-athletes. This retrospective analysis of data reported through the Missouri State High School Activities Association aimed to describe trends in participation and clinical incidence of concussion and provide comparisons of similar sports. […]
Pediatric Traumatic Brain Injury and Healthcare-associated Infections: A Prospective Study on Determinants of Mortality Using Least Absolute Shrinkage and Selection Operator Regression
CONCLUSIONS: Healthcare-associated infections were associated with prolonged critical care burden in mechanically ventilated pediatric patients with moderate to severe TBI. A LASSO model using routinely available clinical variables offers a robust, scalable tool for determinants of mortality in LMIC neurocritical care settings. However, these findings should not be generalized to non-ventilated or mild TBI populations […]
Fighting for safety: head and spine injuries in martial arts presenting to U.S. emergency departments
CONCLUSION: Martial arts-related head, neck, and spine injuries were recorded across all age groups in this analysis, with throwing and flipping techniques among the commonly reported mechanisms. These findings underscore the value of continued attention to safety practices in martial arts participation.
PDE5 inhibition restores mitochondrial function and improves neurobehavioral outcomes after repeated mild blast TBI
Repeated mild traumatic brain injury (rmbTBI) is associated with persistent neurological deficits in military personnel arising from secondary cerebrovascular and metabolic impairments. Critically, there are no FDA-approved therapeutics for rmbTBI. Phosphodiesterase 5 (PDE5) inhibition has been explored in preclinical and clinical TBI studies; however, its exact therapeutic mechanism remains unclear. Recent data demonstrate that PDE5 […]

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