Evidence for a diagnostic distinction between functional seizures and functional motor symptoms from the TriNetX electronic health record database

February 26, 2026

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“False dichotomies” and “FND fundamentalists”: an international mixed methods exploration of clinician and rheumatology patients’ views and experiences of functional neurological disorder (FND) co-diagnoses
Study Overview The investigation into patient and clinician perspectives regarding Functional Neurological Disorder (FND) and its associated challenges represents a vital contribution to the understanding of this complex condition. The study employed an international mixed methods framework, combining qualitative and quantitative approaches to gather comprehensive data on the experiences and attitudes of both patients diagnosed… Read more: “False dichotomies” and “FND fundamentalists”: an international mixed methods exploration of clinician and rheumatology patients’ views and experiences of functional neurological disorder (FND) co-diagnoses
Medically refractory epilepsy comorbid with psychogenic non-epileptic seizures and intellectual disability in a patient with balanced t(14;X) translocation: a case report
Patient Profile and Clinical Background The patient discussed in this case report is a young individual with a complex clinical history characterized by multiple neurological and psychological challenges. At the time of evaluation, the patient was a 10-year-old male with a confirmed diagnosis of medically refractory epilepsy. His seizures were resistant to various antiepileptic medications,… Read more: Medically refractory epilepsy comorbid with psychogenic non-epileptic seizures and intellectual disability in a patient with balanced t(14;X) translocation: a case report
From Positive Sign to Self-Management: Real-Time Interruption Training in Functional Seizures
Understanding Functional Seizures Functional seizures, often referred to as psychogenic non-epileptic seizures (PNES), are episodes that resemble epileptic seizures but are not caused by abnormal electrical discharges in the brain. Instead, these episodes are linked to psychological factors and often occur in individuals who have underlying stress or emotional distress. One notable aspect of functional… Read more: From Positive Sign to Self-Management: Real-Time Interruption Training in Functional Seizures
“False dichotomies” and “FND fundamentalists”: an international mixed methods exploration of clinician and rheumatology patients’ views and experiences of functional neurological disorder (FND) co-diagnoses
Study Overview The investigation into functional neurological disorder (FND) and its management embodies a complex interplay of clinician and patient perspectives. The study aimed to elucidate the experiences and attitudes of both rheumatology patients diagnosed with FND and the clinicians treating them. By employing an international mixed methods approach, the research gathered quantitative and qualitative… Read more: “False dichotomies” and “FND fundamentalists”: an international mixed methods exploration of clinician and rheumatology patients’ views and experiences of functional neurological disorder (FND) co-diagnoses
Medically refractory epilepsy comorbid with psychogenic non-epileptic seizures and intellectual disability in a patient with balanced t(14;X) translocation: a case report
Case Presentation A 24-year-old male presented with a complex medical history characterized by medically refractory epilepsy, psychogenic non-epileptic seizures (PNES), and intellectual disability. The patient had a confirmed balanced translocation of chromosomes 14 and X, specifically a t(14;X), which has been associated with various neurological disorders and developmental delays. His parents reported that the patient… Read more: Medically refractory epilepsy comorbid with psychogenic non-epileptic seizures and intellectual disability in a patient with balanced t(14;X) translocation: a case report

Multi-Organ Inflammatory and Endocrine Crosstalk Shapes the Early Brain Response to Combined Burn and Blast Injury
The pathology of concomitant burn and traumatic brain injury remains poorly defined, despite their frequent co-occurrence in military settings and the potential for deleterious synergy. To address this gap, we combined established models of blast-induced mild traumatic brain injury and 15% total body surface area flame burn to approximate a common combat-related trauma and examined […]
Seatbelt Use and Traumatic Brain Injury Outcomes After Pediatric Motor Vehicle Collisions
CONCLUSION: Abnormal CT findings were less frequent with seatbelt use, ED TBI severity did not differ significantly. Missing data, limited sample size, and unmeasured crash characteristics constrain causal interpretation.
Primary language as a moderator of social integration and functional independence after traumatic brain injury in U.S. older adults
CONCLUSION: Primary language plays a moderating role in the link between social integration and functional independence post-TBI. These findings highlight the need for culturally and linguistically tailored interventions to improve outcomes for older adults with TBI.
Assessing the relevance of test of memory malingering (TOMM) trial 2 performance after failure of trial 1 among veterans with self-reported histories of mild traumatic brain injury
Objective: Despite empirically established cut scores for Trial 1 of the Test of Memory Malingering (TOMM), the interpretive significance of failing Trial 1 while passing Trial 2 remains equivocal, possibly due to the original manual's emphasis on Trial 2. This study examined whether individuals with a Trial 1 fail/Trial 2 pass pattern demonstrate cognitive profiles […]
From injury to degeneration: delayed lipid-mediated neurotoxicity in a human astrocyte traumatic brain injury in-a-dish model
Traumatic brain injury (TBI) is a major cause of long-term neurological disability, and repeated mild TBI (rmTBI) is increasingly linked to chronic neurodegeneration. Clinical evidence suggests that rmTBI creates a prolonged window of vulnerability to further injury. However, the astrocyte-intrinsic mechanisms that convert repeated mechanical stress into delayed neuronal injury remain poorly defined. In particular, […]

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