Evidence for a diagnostic distinction between functional seizures and functional motor symptoms from the TriNetX electronic health record database

February 26, 2026

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Long-Term Outcomes After Slowly Resorbable P4HB Mesh Implantation: A Multicenter Analysis From European Registry
Study Overview The investigation examined the long-term effectiveness and safety of P4HB mesh, a type of biodegradable implant, in surgical applications. This multicenter study utilized data from a European registry, which involved diverse medical centers to gather comprehensive information regarding the outcomes associated with the use of P4HB mesh. The research aimed to evaluate both… Read more: Long-Term Outcomes After Slowly Resorbable P4HB Mesh Implantation: A Multicenter Analysis From European Registry
Combined intervention of Akkermansia muciniphila and sodium butyrate ameliorates oxaliplatin-induced peripheral neuropathy by suppressing neuroinflammation and reducing serum neurofilament light chain
Mechanisms of Action The intervention involving Akkermansia muciniphila and sodium butyrate operates through several interconnected mechanisms that target the underlying causes of oxaliplatin-induced peripheral neuropathy (OIPN). OIPN is characterized by neuroinflammation and the degeneration of nerve fibers, leading to debilitating symptoms in cancer patients undergoing chemotherapy. The therapeutic agents of interest contribute to ameliorating these… Read more: Combined intervention of Akkermansia muciniphila and sodium butyrate ameliorates oxaliplatin-induced peripheral neuropathy by suppressing neuroinflammation and reducing serum neurofilament light chain
Enhancing the endocannabinoid system to treat residual disease in relapse-free multiple sclerosis
Endocannabinoid System and Multiple Sclerosis The endocannabinoid system (ECS) consists of a network of receptors, endogenous cannabinoids, and metabolic enzymes that collectively play a crucial role in maintaining homeostasis in various physiological processes. In the context of multiple sclerosis (MS), a chronic autoimmune disease characterized by demyelination in the central nervous system, the ECS is… Read more: Enhancing the endocannabinoid system to treat residual disease in relapse-free multiple sclerosis
Pediatric-Onset Multiple Sclerosis Presenting With Persistent Vertigo, Ataxia, and Optic Nerve Atrophy in a 15-Year-Old Girl: A Case Report
Study Overview The case report highlights an unusual presentation of pediatric-onset multiple sclerosis (POMS) in a 15-year-old female patient who exhibited persistent vertigo, ataxia, and optic nerve atrophy as primary symptoms. This scenario emphasizes the complexities involved in diagnosing POMS, a rare form of multiple sclerosis that typically manifests in children and adolescents, distinguishing it… Read more: Pediatric-Onset Multiple Sclerosis Presenting With Persistent Vertigo, Ataxia, and Optic Nerve Atrophy in a 15-Year-Old Girl: A Case Report
Predictors of Discontinuation of Angiotensin Converting Enzyme Inhibitors Use Among Medicare Beneficiaries Using Sodium-Glucose Cotransporter 2 Inhibitors
Study Overview The research investigates the discontinuation rates of Angiotensin Converting Enzyme (ACE) inhibitors among Medicare beneficiaries who are concurrently using Sodium-Glucose Cotransporter 2 (SGLT2) inhibitors. ACE inhibitors are commonly prescribed for managing hypertension and protecting kidney function in patients with diabetes, while SGLT2 inhibitors are increasingly utilized for their effects on glycemic control and… Read more: Predictors of Discontinuation of Angiotensin Converting Enzyme Inhibitors Use Among Medicare Beneficiaries Using Sodium-Glucose Cotransporter 2 Inhibitors

Assessing head injury risk and neuroprotective effect of ketone monoester supplementation in military airborne training
Warfighters face significant risk of mild traumatic brain injury (mTBI) during operations and training. We performed a double-blind, randomized, placebo-controlled trial to: (1) determine head strike (HS) incidence, during US Army Basic Airborne Course's Improved Swing Landing Trainer (ISLT) training, (2) test protective efficacy of ketone monoester (KME) supplementation, and (3) assess blood-based mTBI biomarker […]
Role of Polygenic Risk Scores in Predicting Cognitive Functioning after Mild Traumatic Brain Injury: A TRACK-TBI Study
Patients with traumatic brain injury (TBI) and Glasgow Coma Scale scores of 13-15 (historically called mild TBI [mTBI]) commonly experience changes in cognitive functioning, including processing speed, memory, and executive functioning. In a prospective sample (N = 523) of individuals of European descent who had been treated in a U.S. level 1 trauma center for […]
Utility of Amyloid Beta and Tau Positron Emission Tomography Scans for Identifying Early-Stage Neurodegenerative Changes in Former Professional Football Players and Healthy Controls: Results from the Brain Health Initiative
The aim of this study is to determine if there is a difference in tau and amyloid beta (Aβ) deposition on positron emission tomography (PET) scans between former players and controls, and if there is a differential association of the tau and Aβ deposition with concussion symptom burden. Participants completed the Rivermead Post-Concussion Questionnaire (RPQ) […]
Tau-PET imaging and blood biomarkers reveal early tauopathy in special operations forces exposed to repetitive blast
Repeated low-intensity blast overpressure exposures, frequently sustained by Special Operations Forces during breaching, combat training, and weapons use, are thought to initiate tau-related neurodegenerative changes that may remain clinically silent for years. The long-term impact of cumulative blast overpressure on brain health is poorly understood, and sensitive biomarkers are needed for early detection and monitoring […]
Psychological Resilience Moderates Autonomous Motivation After Mild Traumatic Brain Injury: A Randomized Controlled Trial of a Remote Walking Program
CONCLUSION: The remote walking program did not increase autonomous motivation on average, but controlled motivation was higher at 6 months. Higher baseline resilience strengthened the program's effect on autonomous motivation. Screening for resilience and integrating resilience-building components may enhance motivational benefits and support long-term adherence in rehabilitation.

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