Functional Neurologic Symptoms in Multiple Sclerosis: Estimated Prevalence and Associated Comorbidities

February 23, 2026

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Mechanism of change in functional neurological (motor) disorder: a pilot study using a single-case experimental design
Study Overview This pilot study was designed to investigate the mechanisms underlying changes in functional neurological disorder (FND), specifically motor symptoms, by employing a single-case experimental design. FND is characterized by neurological symptoms that cannot be attributed to any underlying organic or structural pathology, often resulting in significant disability for affected individuals. The focus of… Read more: Mechanism of change in functional neurological (motor) disorder: a pilot study using a single-case experimental design
Stances and levels in the explanation of functional neurological disorder
Understanding Functional Neurological Disorder Functional neurological disorder (FND) is characterized by neurological symptoms that manifest without an identifiable organic cause. These symptoms can include motor dysfunctions such as weakness or paralysis, sensory disturbances, and non-epileptic seizures. Unlike traditional neurological disorders, where identifiable pathologies like tumors or lesions explain the conditions, FND presents a complex interplay… Read more: Stances and levels in the explanation of functional neurological disorder
Non-invasive ventilation (NIV) and high-flow nasal therapy (HFNT) in palliative care: a critical narrative review
Context and Relevance Non-invasive ventilation (NIV) and high-flow nasal therapy (HFNT) have emerged as significant therapeutic modalities in palliative care, particularly for patients suffering from chronic respiratory conditions. These techniques aim to alleviate dyspnea and improve the quality of life for individuals with advanced illnesses, where traditional invasive methods may pose additional burdens or risks.… Read more: Non-invasive ventilation (NIV) and high-flow nasal therapy (HFNT) in palliative care: a critical narrative review
Mechanism of change in functional neurological (motor) disorder: a pilot study using a single-case experimental design
Study Overview This pilot study investigates the mechanisms driving changes in individuals diagnosed with functional neurological disorder (FND), specifically focusing on motor symptoms. Unlike traditional neurological disorders, FND is characterized by the presence of neurological symptoms that cannot be fully explained by medical conditions or structural abnormalities. The pilot study aims to combine clinical observation… Read more: Mechanism of change in functional neurological (motor) disorder: a pilot study using a single-case experimental design
Stances and levels in the explanation of functional neurological disorder
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) represents a complex interaction of neurological and psychological factors that lead to significant movement and sensory symptoms that are not explained by conventional neurological conditions. Unlike structural or biochemical disorders, FND showcases how the brain may malfunction in processing voluntary movement and sensations, often resulting in symptoms… Read more: Stances and levels in the explanation of functional neurological disorder

Irritability Among Veterans With Chronic Mild Traumatic Brain Injury: Psychological and Sensory Neurophysiological Factors
CONCLUSIONS: Irritability was a prominent symptom among veterans with chronic mTBI and was strongly associated with PTSD and pain, with additional contributions from auditory processing. These findings suggest that irritability in chronic mTBI is multifactorial, reflecting both psychological and sensory neurophysiological factors.
Safety, accuracy, empathy, information quality, and readability of publicly accessible LLM-based chatbots for traumatic brain injury and concussion questions: a cross-sectional comparative study
CONCLUSION: LLM-based chatbots generated responses that were generally rated as safe and informative by expert evaluators, but potentially harmful advice and readability problems remained. These findings characterize expert-rated response performance and do not establish patient comprehension, educational effectiveness, or clinical benefit. LLM-based chatbots may have potential as supplementary sources of patient-facing health information, but they […]
Whole-blood point-of-care glial fibrillary acidic protein and ubiquitin C-terminal hydrolase L1 biomarkers after traumatic brain injury in the US: a prospective diagnostic prediction of intracranial injury on head CT
BACKGROUND: Biomarkers like glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) are being globally recommended as a valuable component in the evaluation of acute TBI. Having a regulatory-approved whole-blood test is imperative to provide consistent and democratized approach to healthcare. This prospective, national multicenter cohort trial (NCT04171960) evaluated the performance of a […]
Renal dioctophymosis in a free-ranging lesser grison (Galictis cuja): antemortem diagnosis and nephrectomy
Dioctophymosis is caused by Dioctophyme renale, a nematode that primarily affects the right kidney of domestic and wild mammals. This report describes the antemortem diagnosis, surgical treatment, and rehabilitation of a free-ranging lesser grison (Galictis cuja) infected with the parasite. An adult male weighing 1.85 kg was admitted after being struck by a vehicle and […]
Knowledge and practice of evidence-based mild traumatic brain injury guidelines among physicians providing emergency and trauma care in Israel
CONCLUSIONS: In this exploratory sample, gaps in both knowledge and implementation of internationally accepted post-mTBI guidelines were observed among Israeli physicians providing emergency and trauma care. The findings support revisions to national procedures, targeted training, and the development of a coordinated stepped-care pathway that links emergency and primary care with community-based follow-up for all patients […]

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