Functional Neurologic Symptoms in Multiple Sclerosis: Estimated Prevalence and Associated Comorbidities

February 23, 2026

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Diagnostic Overshadowing in Functional Neurological Disorder Leading to a Diagnosis of Acute Motor and Sensory Axonal Neuropathy: A Case Report
Study Overview The investigation conducted in this case report centers on the complex interaction between functional neurological disorder (FND) and acute motor and sensory axonal neuropathy (AMSAN), highlighting the issues surrounding diagnostic overshadowing. The patient, a middle-aged individual with previously documented psychological symptoms, presented with sudden-onset motor weakness and sensory disturbances. This clinical presentation led… Read more: Diagnostic Overshadowing in Functional Neurological Disorder Leading to a Diagnosis of Acute Motor and Sensory Axonal Neuropathy: A Case Report
Personality Disorders in Functional and Idiopathic Dystonia
Personality Profiles in Dystonia Research into personality profiles among individuals suffering from dystonia has revealed compelling insights into how these psychological traits may interact with the neurological manifestations of the disorder. Dystonia itself is characterized by involuntary muscle contractions that lead to abnormal postures or movements, and it can be influenced by a variety of… Read more: Personality Disorders in Functional and Idiopathic Dystonia
Disability, distress and delayed access to care in functional neurological disorder: cross-sectional study from an Australian tertiary clinic
Study Overview This study was conducted to explore the relationship between disability, psychological distress, and the access to care for individuals diagnosed with Functional Neurological Disorder (FND) within an Australian tertiary clinic setting. FND, characterized by neurological symptoms that cannot be attributed to any identifiable medical condition, presents significant challenges both to patients and healthcare… Read more: Disability, distress and delayed access to care in functional neurological disorder: cross-sectional study from an Australian tertiary clinic
CT-guided injection in coccydynia: outcome prediction using MRI findings and CT-injection characteristics
Background and Rationale Coccydynia, characterized by pain in the coccyx region, often results from injury, prolonged sitting, or degenerative changes. This condition can significantly impair quality of life, leading to difficulties in daily activities and a reduced ability to sit comfortably. Traditional management strategies may include conservative treatments like pain medications, physical therapy, and activity… Read more: CT-guided injection in coccydynia: outcome prediction using MRI findings and CT-injection characteristics
Diagnostic Overshadowing in Functional Neurological Disorder Leading to a Diagnosis of Acute Motor and Sensory Axonal Neuropathy: A Case Report
Study Overview This case report investigates the phenomenon of diagnostic overshadowing within the context of Functional Neurological Disorder (FND) that led to a misdiagnosis of Acute Motor and Sensory Axonal Neuropathy (AMSAN). In such cases, the presence of psychological factors can cloud the clinical assessment, resulting in treatments that may not address the underlying issues… Read more: Diagnostic Overshadowing in Functional Neurological Disorder Leading to a Diagnosis of Acute Motor and Sensory Axonal Neuropathy: A Case Report

Outcomes of Integrated Practice Unit Treatment for Mild Traumatic Brain Injury and Co-occurring Conditions Among Veterans
CONCLUSIONS: The IPU approach to the evaluation and management of persistent post-mTBI symptoms and co-occurring conditions suggests significant symptom reduction and improvement in wellness in a veteran population.
Relating brain function to cognitive-visuomotor integration performance in working-aged adults with persisting concussion symptoms
INTRODUCTION: In everyday life we interact with our environment in an indirect way, where there is a mapping between the viewed goal of our action and the required movement (e.g., using a computer mouse). Such tasks require cognitive- motor integration (CMI), where rules dictate the relationship between perception and action. Previous research with primarily young […]
Advancing biomarker development for chronic traumatic encephalopathy: Summary and recommendations from the 2025 Leon Thal Summit
The 2025 Leon Thal Summit convened an international panel of clinicians, neuroscientists, neuropathologists, and neuroimaging specialists to evaluate the current state of biomarker development for chronic traumatic encephalopathy (CTE) and to outline priorities for advancing translational research for this important area. Discussions integrated emerging findings from longitudinal cohorts, new molecular and neuroimaging approaches, expanding post […]
A Systematic Review of Peer-Reviewed Studies on Preventing Sport-Related Concussion (SRC) in Adult Football (Soccer): Mapping Sparce Evidence of Rule Changes and Head-Neck Training
Background/Objectives: Acute health impacts and longer-term sequelae of sport-related concussion (SRC) are recognized concerns in football (soccer), warranting investigation of interventions to reduce the incidence. The purpose of this study was to identify, synthesize and evaluate interventions used in preventing sport-related concussion (SRC) in adult soccer players. Methods: Five databases (MEDLINE, CINAHL, Embase, SPORTDiscus, PsycINFO) […]
Neuronal p38a knockout protects against neurological consequences following repetitive mild traumatic brain injury
Mild traumatic brain injuries (mTBI) can substantially impact quality of life, and repetitive mTBIs (rmTBI) can amplify injury effects compared to a single injury. However, effective clinical treatments remain elusive, largely due to an incomplete understanding of the underlying injury mechanisms. Neuroinflammation has emerged as a key contributor to worse functional outcomes after mTBI/rmTBI. While […]

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