Objective To evaluate whether a retinal spectral-domain optical coherence tomography (SD-OCT) assessment at baseline is associated with long-term disability worsening in people with multiple sclerosis…

A 57-year-old woman presented with a 1-year history of frequent, sharp, prickling pain in the right oropharynx, often triggered by swallowing or talking. Oxcarbazepine, pregabalin,…

Objective To determine contemporary trends in case fatality, discharge destination, and admission to long-term care after acute ischemic stroke and intracerebral hemorrhage (ICH) using a…

A 23-year-old patient with multiple sclerosis on dimethyl fumarate presented with new-onset left-sided hearing loss, vertigo, and tinnitus.1 Prior to presentation, serial imaging showed no…

García-Azorín et al.1 report on their detailed and cross-sectional appraisal of delayed alcohol-induced headache in approximately 1,100 university students. Their detailed phenotyping substantially deepens and…

Objective To define the clinical characteristics, management, and outcome of neurologic immune-related adverse events (n-irAEs) of immune checkpoint inhibitors (ICIs). Methods Systematic review of the…

There is general recognition that stroke mortality has declined over the past 2 decades.1,2 Two important questions, whether this decline holds true for all forms…

Multiple sclerosis (MS) exhibits heterogeneity in its clinical course, making it difficult for patients and their physicians to forecast the disease course and to make…

In 2010, a novel agent, ipilimumab, demonstrated improved survival rates in patients with previously untreatable metastatic melanoma.1 Ipilimumab was approved by the Food and Drug…

Articles appearing in the February 2021 issue Read article at journal’s website