MyNeuroNews

Sleep disturbances are mainly improved by deep brain stimulation of the subthalamic nucleus

Lucia Ricciardi, Chiara Sorbera, Marianna Barbuto, Francesca Morgante January 19, 2019

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STOP 101: A Phase 1, Randomized, Open‐Label, Comparative Bioavailability Study of INP104, Dihydroergotamine Mesylate (DHE) Administered Intranasally by a I123 Precision Olfactory Delivery (POD®) Device, in Healthy Adult Subjects

Stephen B. Shrewsbury, Maria Jeleva, Kelsey H. Satterly, Jason Lickliter, John Hoekman January 19, 2019

Objective

Investigate the safety and pharmacokinetics (PK) of INP104, intranasal dihydroergotamine mesylate (DHE) administered via a Precision Olfactory Delivery (POD^®) device, (Impel NeuroPharma, Seattle, WA) vs intravenous (IV) DHE and DHE nasal spray (Migranal^®) in healthy adult subjects.… Read More...

Optimism, Pessimism, and Migraine: A Cross‐Sectional, Population‐Based Study

Mario F.P. Peres, Arão Belitardo Oliveira, Juliane P. Mercante, Helder H. Kamei, Patricia R. Tobo, Todd D. Rozen, Morris Levin, Dawn C. Buse, Giancarlo Lucchetti January 19, 2019

Background

Optimism and pessimism are related to several mental health and brain disorders, are significant predictors of physical and psychological health outcomes, and implicated as psychosocial determinants of the pain experience. Despite this promising evidence, limited information is available on optimism and pessimism in headache disorders.… Read More...

CGRP ligand and receptor monoclonal antibodies for migraine prevention: Evidence review and clinical implications

David W Dodick January 19, 2019

Cephalalgia, Ahead of Print.

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Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth

Olivier Cerles, Tânia Cristina Gonçalves, Sandrine Chouzenoux, Evelyne Benoit, Alain Schmitt, Nathaniel Edward Bennett Saidu, Niloufar Kavian, Christiane Chéreau, Camille Gobeaux, Bernard Weill, Romain Coriat, Carole Nicco and Frédéric Batteux January 19, 2019

The endogenous cholinergic system plays a key role in neuronal cells, by suppressing neurite outgrowth and myelination and, in some cancer cells, favoring tumor growth. Platinum compounds are widely used as pa…

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