The role of the non-coding genome in epilepsy has primarily been focused on the widespread disruption of microRNA (miRNA) expression and function [1]. However, the involvement of long non-coding RNAs (lncRNAs) in epilepsy remains unknown. LncRNAs are a heterogeneous group of non-coding transcripts (longer than 200 nt) that play roles in many biological processes [2] and comprise the largest portion of the mammalian non-coding transcriptome.… Read More...

Background: Intracerebral hemorrhage is a devastating disease. In recent years, the association of between baseline serum ferritin and prognosis of intracerebral hemorrhage is an interesting issue. Although some of the studies have shown that baseline serum ferritin can predict the prognosis of intracerebral hemorrhage, there is no clear evidence that baseline serum ferritin can be used as an independent predictor of intracerebral hemorrhage.… Read More...

Stroke is among the leading causes of mortality and morbidity in the world. Besides the identified risk factor, Ischemic stroke evidence show drug use develops or exacerbates the atherosclerotic process. The current study aimed at comparing cerebrovascular ultrasounds’ changes in addicted and nonaddicted people who developed ischemic stroke.… Read More...

Su et al. demonstrate that VTA GABA neurons signal aversion to itch and DA neurons mediate scratching-associated reward. Differential activation and function of VTA neurons may underlie the progression of vicious itch-scratch cycles.

Multiple Sclerosis Journal, Ahead of Print.

Focal impaired awareness seizure (FIAS) is a clinical phenomenon with a prevalence of 0.8% that manifests as epileptic discharges commonly located in the amygdala-hippocampal complex. It can cause visual delusions and olfactory, auditory, or affective hallucinations [1]. Obstructive sleep apnea (OSA) is common in patients with epilepsy [2].… Read More...

Cephalalgia, Ahead of Print.

Cephalalgia, Ahead of Print.

Cephalalgia, Ahead of Print.

The objective of the study by Papadopoulos et al. was to evaluate the effect of various parameters such as temperature, focused ultrasound (FUS) energy, FUS frequency, acoustic power, and microbubble administration on tenecteplase (TNK)-tissue plasminogen activator-mediated thrombolysis and therefore, to establish a treatment protocol that maximize thrombolysis efficacy.… Read More...