Abstract

Background

Identification and characterization of Parkinson’s disease (PD) in its prodromal stage is crucial.

Objective

The objective of this study was to investigate the association between motor function and the probability of prodromal PD in a community‐dwelling older population.

Methods

We used data from a population‐based cohort of older adults (HELIAD study).… Read More...

Abstract

Background

Identification and characterization of Parkinson’s disease (PD) in its prodromal stage is crucial.

Objective

The objective of this study was to investigate the association between motor function and the probability of prodromal PD in a community‐dwelling older population.

Methods

We used data from a population‐based cohort of older adults (HELIAD study).… Read More...

Dementia, Ahead of Print.

Dementia, Ahead of Print.

Abstract

To improve the diagnostic accuracy of electroencephalography (EEG) criteria for nonconvulsive status epilepticus (NCSE), external validation of the recently proposed Salzburg criteria is paramount. We performed an external, retrospective, diagnostic accuracy study of the Salzburg criteria, using EEG recordings from patients with and without a clinical suspicion of having NCSE.… Read More...

American Journal of Alzheimer’s Disease &Other Dementias®, Ahead of Print.
The aim of this study is to investigate the impact of optimal antihypertensive medication on cognitive function. In this 6-month clinical trial, 248 adults were randomly selected by a registry of hypertensive-treated patients (based on a National Hypertension Treatment Program), followed health centers located in Rafsanjan County, Southeast, Iran.… Read More...

American Journal of Alzheimer’s Disease &Other Dementias®, Ahead of Print.
A recent review of Cochrane meta-analyses on psychosocial interventions (PIs) concludes that clinical trials fail to confirm PIs effective for all types of dementia at every stage of the disease. This article describes how and to what extent it is necessary to identify treatment indications when researching PIs and employing them in clinical practice.… Read More...

American Journal of Alzheimer’s Disease &Other Dementias®, Ahead of Print.
Background:We assessed implicit and explicit emotion in older patients with dementia using biosignals.Methods:Fifty patients with dementia and 34 healthy individuals watched 3 videos that aimed to elicit various emotional responses. Electroencephalogram and heart rate variability were recorded.Results:Patients with dementia experienced less fun and more fear than controls.… Read More...

Background: Some studies have demonstrated the high impact of headache and migraine in several areas of children and adolescents’ life. In recent years, there has been an increase in scientific interest in the relationship between migraine and emotional regulation, investigating the possible consequences of emotional dysregulation on physical and mental health.… Read More...

Thrombosis is the main pathogenesis of acute ischemic stroke (AIS). The main treatments for stroke either have limited efficacy or increase the risk of bleeding. ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) is a metal protease that can effectively break down VWF (Von Willebrand Factor, VWF), the key factor in thrombus formation.… Read More...