Tag:

human brain

Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Erratum: Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview The research presented focuses on the development and validation of an advanced animal …

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Traumatic brain injury
Sex-dependent blood-brain barrier alterations following repeated mild blast traumatic brain injury at varying inter-injury intervals

by myneuronews June 1, 2025

by myneuronews June 1, 2025

Study Overview The investigation focused on the impact of repeated mild blast traumatic brain injuries …

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Functional neurological disorders
Biochemical investigation of pathogenic missense mutations of human 4-amino butyrate aminotransferase towards the understanding of the molecular pathogenesis of GABA transaminase deficiency

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Biochemical Characterization of Mutant 4-Aminobutyrate Aminotransferase In this detailed study, researchers focused on the biochemical …

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Traumatic brain injury
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Impact of Mild Traumatic Brain Injury Mild traumatic brain injury (mTBI) poses significant challenges not …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Hippocampal Function and Adult Neurogenesis The hippocampus is a critical brain region known for its …

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Impact of surgery in patients with multiple sclerosis: a nationwide cohort study
Study Overview The investigation aimed to evaluate the influence of surgical interventions on individuals diagnosed…
Effects of Electrical Stimulation Therapy for Residual Foot Drop Following Lumbar Spinal Stenosis Surgery: A Case Report
Study Overview The study investigates the effects of electrical stimulation therapy on patients suffering from…
Navigating Fabry Disease in a Military Aviator
Understanding Fabry Disease Fabry disease is a rare genetic disorder that results from a deficiency…
Pituitary Mimic: Sellar Meningioma in a Patient Undergoing Fertility Therapy
Background of Sellar Meningiomas Sellar meningiomas are a specific type of tumor that originates from…
Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) After Polypropylene Mesh Implantation – Protocol of a Pilot Study for Diagnostics and Treatment
Background of ASIA Syndrome Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) encompasses a spectrum of…

A one year longitudinal study of cortical myelination changes following pediatric mild traumatic brain injury
The impact of pediatric mild traumatic brain injury (pmTBI) on cortical (i.e., grey matter) myelination is not yet understood, especially for interactions with neurodevelopment. The current study examined the impact of pmTBI on cortical myelination relative to healthy controls (HC) by estimating myelin content using the T(1)w/T(2)w ratio method. Data were obtained from pmTBI (N […]
Attention-Deficit/Hyperactivity Disorder as a Mediating Variable for Invalid Baseline Profiles on the ImPACT
CONCLUSIONS: Our study suggests that the relationship between age and ImPACT validity is explained by the presence of ADHD. Results support adjusting ImPACT's validity thresholds for individuals with ADHD.
Integrative Constraint-Based Modeling and Proteomics Uncover Astrocytic Metabolic Adaptations to the Post-TBI Microenvironment
Traumatic brain injury (TBI) is a major neurological condition affecting millions of individuals each year. Mild TBI (mTBI) manifests differently, with some individuals experiencing persistent, debilitating symptoms while others recover more rapidly. Despite its classification as "mild," mTBI leads to both short- and long-term neurological effects, many of which occur due to functional changes in […]
Repetitive head impact exposure in collegiate wrestling practices using instrumented mouthguard technology
Collegiate wrestling presents a higher risk of concussion than American football. However, there is limited research on repetitive head impact exposure in wrestling, and how it compares to football is unknown. Therefore, this study explores repetitive head impacts in Division 1 collegiate wrestlers (n = 11, age = 20 ± 2 years, 125-285 lbs) during […]
Association between concussion-reporting intention and reporting behavior in a simulated game setting
CONCLUSIONS: Concussion-reporting behavior in a novel, first-person simulated in-game experience is higher among individuals with higher baseline concussion-reporting intention. This approach may offer promise for evaluating concussion-reporting intention and concussion-reporting behavior via interactive video simulation.